Web-based lab to study the decision to use antidepressants for the elderly

描述（由申请人提供）：拟议项目开发了一个基于网络的软件应用程序和调查，其中包含患者-病例描述和问卷，以便于研究患者种族和老年人使用抗抑郁药治疗的决定。结果将指导进一步的研究，并为制定干预措施提供信息。基于网络的应用程序将是一个在线医疗保健决策实验室，支持多年的研究。这项调查对于随后进行的关于患者种族和抗抑郁治疗的研究至关重要。该项目为期两年，有四个具体目标。目标1是软件开发：我们设计软件，准确地测量反应时间，实现阈下启动，并实现因子调查。该软件还执行管理网站和数据收集的标准任务。目的2是开发患者病例的析因表示：我们将患者病例设计为析因调查，旨在改变患者线索，以便抑郁症治疗的概率跨越单位间隔。析因调查对后续研究至关重要。目的3是制定医生问卷：我们制定了一份问卷，包括关于医生人口统计学、经验和态度的问题：该目的的目标是促进收集与使用AT的决定相关的医生信息，但将整体在线调查保持在40分钟以内。目的4是测试整体可行性：我们测试在线应用的调查，以确保整体可行性使用的样本家庭执业医生。这是对所有组件的测试，包括采样策略和基于Web的应用程序。该测试的目标是大于50%的响应率和识别预测招募和脱落的医生特征：后续研究设计的基本信息。相关性：众所周知，抑郁症影响老年人，治疗因患者种族而异，医生的决定部分解释了这种差异。这是一个知识空白，必须填补提供补救措施，原因不明。要知道为什么，我们必须了解患者种族如何在认知水平上影响医生的决策。拟议的项目启动了一项计划，通过开发必要的方法和设施，将心理学的基本知识转化为临床相关研究，以回答患者种族如何影响治疗老年人抑郁症的决定的问题。众所周知，抑郁症影响老年人，治疗因患者种族而异，医生的决定部分解释了这种差异。这是一个知识空白，必须填补提供补救措施，原因不明。要知道为什么，我们必须了解患者种族如何在认知水平上影响医生的决策。拟议的项目启动了一项计划，通过开发必要的方法和设施，将心理学的基本知识转化为临床相关研究，以回答患者种族如何影响治疗老年人抑郁症的决定的问题。

DESCRIPTION (provided by applicant): The proposed project develops a web-based software application and survey containing both patient-case descriptions and questionnaire to facilitate research of patient race and the decision to use antidepressant treatment among the elderly. Results will direct further study and inform the development of interventions. The web-based application will be an online healthcare decision lab, supporting research for many years. The survey is essential to the ensuing research on patient race and antidepressant treatment. The project spans two years and has four specific aims. AIM 1 is software development: we design software that accurately measures response times, implements subliminal priming, and implements factorial surveys. The software also performs the standard tasks of governing the website and data collection. AIM 2 is develop a factorial representation of patient cases: we design patient cases as a factorial survey intended to vary in patient cues such that the probability of the treatment for depression spans the unit interval. The factorial survey is essential to the ensuing research. AIM 3 is develop physician questionnaire: we develop a questionnaire comprising questions regarding physician demographics, experience, and attitudes: the goal of this aim is to facilitate collection of physician information related to the decision to use AT, but keep the overall online survey to less than 40 minutes. AIM 4 is test overall feasibility: we test the online application of the survey to assure overall feasibility using a sample of family practice physicians. This is a test of all components including the sampling strategy and the web-based application. The goals of this test are a greater than 50% response rate and identification of physician characteristics that predict recruitment and dropout: essential information to the design of the subsequent study. Relevance: It is known that depression impacts the elderly, treatment differs by patient race, and physician decisions partially explain the disparity. It is not known why-a knowledge gap that must be filled to provide remedy. To know why, we must understand how patient race influences the decision-making of physicians at a cognitive level. The proposed project initiates a program that translates basic knowledge from psychology into clinically relevant research by developing the requisite methods and facility to answer the question of how patient race influences the decision to treat the elderly for depression. It is known that depression impacts the elderly, treatment differs by patient race, and physician decisions partially explain the disparity. It is not known why-a knowledge gap that must be filled to provide remedy. To know why, we must understand how patient race influences the decision-making of physicians at a cognitive level. The proposed project initiates a program that translates basic knowledge from psychology into clinically relevant research by developing the requisite methods and facility to answer the question of how patient race influences the decision to treat the elderly for depression.