Deep South Partnership for Prevention of CVD Disparities

描述(由申请人提供)： 我们的合作伙伴关系建立在少数族裔服务系统(库珀绿色医院、矿区医学会和塔斯基吉大学)和研究密集型医疗中心-阿拉巴马大学伯明翰分校(UAB)之间的富有成效的关系之上，专注于心血管疾病预防、护理和结果方面的不平等。我们的团队有能力接受初始投资，并建立一个持续的科学生产力和教育推广计划。通过每个跨学科项目，生物伦理考虑和社区合作伙伴关系创造了一个具有凝聚力的计划。 研究目标：以消除心血管疾病差异为长期目标，(1)调查遵守循证指南和对提供者的信任措施与感知歧视之间的联系；(2)开发和测试基于改良的适合非裔美国人文化的DASH饮食的抗高血压干预措施；(3)表征传统非裔美国人食品的生物活性多酚成分，随后开发、传播和评估建立在文化上适当的结果翻译基础上的饮食教育计划；以及(4)开发和测试在低识字率人群中戒烟的干预措施，使用与识字率相适应的电子工具，根据使用者对变化的准备情况定制。教育目标：为新出现的差异研究人员提供：(1)临床和结果研究的基本工具，包括生物统计学、流行病学、心理测量学、行为干预、公平和差异评估；以及(2)基本的生命伦理问题、原则、态度和做法的知识，这些问题、原则、态度和做法是在文化多样性和服务不足的人群中进行公平研究的基础。在南方腹地，我们将推进缩小差距的研究，培训一批新的差距研究人员，并建立我们通过社区赋权和社区健康顾问来转化研究的模式。

DESCRIPTION (provided by applicant): Our PARTNERSHIP builds on a productive relationship between a minority serving system (Cooper Green Hospital, the Mineral District Medical Society, and Tuskegee University) and a research-intensive medical center, the University of Alabama at Birmingham (UAB) to focus on inequities in CVD prevention, care, and outcomes. Our team has the demonstrated ability to take an initial investment and establish a sustained program of scientific productivity and educational outreach. Woven through each interdisciplinary project, bioethical considerations and community partnerships create a cohesive program. RESEARCH AIMS: with a long-term goal of eliminating CVD disparities, (1) investigate associations between adherence to evidence-based guidelines and measures of trust in providers and of perceived discrimination; (2) develop and test an anti-hypertensive intervention based on the DASH diet modified to be culturally appropriate for African-Americans; (3) characterize the bioactive polyphenolic composition of traditional African-American foods, followed by the development, dissemination, and evaluation of dietary education programs built on culturally appropriate translation of results; and (4) develop and test an intervention for tobacco smoking cessation in a low-literacy population, using literacy-appropriate electronic tools, tailored to the user's readiness for change. EDUCATION AIMS: provide emerging disparity researchers with: (1) basic tools of clinical and outcomes research, including biostatistics, epidemiology, psychometrics, behavioral interventions, equity and disparity assessment; and (2) knowledge of fundamental bioethical issues, principles, attitudes, and practices underlying equitable research with culturally diverse and underserved populations. Set in the DEEP SOUTH, we will move forward with disparity-reducing research, training a cadre of new disparity researchers, and building our model of translating research through community empowerment and Community Health Advisors.