Clinical Science Research Core B

临床科学研究核心的目的是：1)加强和促进与营养有关的

The purposes of the Clinical Science Research Core are: 1) to enhance and facilitate nutrition-related clinical research, 2) to provide training for young investigators in such research, and 3) to provide basic researchers with ready access to clinical research technology so that hypotheses based on non-human models can be tested in humans. Moreover, it is expected that the Clinical Science Research Core will play a central role in stimulating patient-oriented nutrition research at Washington University. The Clinical Science Research Core will provide state-of-the-art methods and services to support clinical research organized through three sub-cores: Metabolic Kinetics Sub-core (stable isotope tracers and mathematical modeling of metabolic kinetics); Body Composition and Metabolic Imaging Sub-core (Mangnetic resonance imaging (MRI), Magnetic resonance spectroscopy (MRS), Positron emission tomography (PET), Dual energy x-ray absorptiometry (DEXA); Cardiovascular Assessment Sub-core (endothelial function, carotid artery intima-media thickness, echocardiograms, indirect calorimetry, exercise assessment and training). A large number of current and future research projects will require the use of all 3 sub-cores for a complete characterization of subjects. The consolidation of these services within one Core will help ensure overall quality, limit inappropriate research efforts, increase cost-effectiveness and facilitate the use of a range of services that would otherwise be difficult for investigators to obtain.