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中文摘要
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描述(由申请人提供):第15届戈登时间生物学研究会议将于2007年5月6日至11日在法国奥索瓦Paul Langevin中心举行,现申请部分资助。近年来,人体内部时钟(昼夜节律时钟)在调节和调节时间生理方面的重要性日益明确,因此,人们致力于分析昼夜节律过程的机制。认识到昼夜节律在人类健康和疾病中所起的关键作用,加上最近关于产生和调节昼夜节律系统的分子机制的具有里程碑意义的发现,导致了该领域的显著扩展。今天,时间生物学研究吸引了来自广泛学科的大量研究人员,包括神经科学、分子遗传学、光生物学、计算生物学和新陈代谢,以及睡眠医学、精神病学、肿瘤学和老年学。戈登时间生物学会议的目的是:1)为快速发展的时间生物学领域提供一个讨论和确定一般原则的论坛。2)促进时间生物学各分支学科研究人员之间的互动,从而提高整个研究领域的一致性。3)加强年轻和成熟研究人员之间的互动,从而维持高质量的时间生物学研究。4)通过汇集来自许多不同研究小组和国家的科学家,促进国内和国际合作。5)通过将使用模式生物的研究人员与在昼夜节律研究中研究人类受试者的研究人员聚集在一起,促进转化研究。会议将通过聚集来自不同国家、年龄、性别和使用不同研究模式的大约150名科学家来实现这些目标。该计划将侧重于关键研究领域的新发展和新兴发展(见暂定计划)。按照非常成功的戈登会议形式,讲座将分为8个早晚会议,并有充足的讨论时间。四次海报会议将允许参与者展示额外的数据。特别注意实现性别平衡(见讨论领导人)和包括来自非常不同学科的专家,以实现对我们科学前沿的广泛理解和对未来机会的见解。结果将与改善表现为睡眠、情感、认知、神经、代谢、内分泌和肿瘤疾病以及职业健康的功能障碍具有健康相关性。要求为将于2007年5月6日至11日在法国奥索瓦Paul Langevin中心举行的第15届戈登时间生物学研究会议提供部分支持。会议的目标是将不同的领先研究人员聚集在一起,专注于关键研究领域的新兴发展,以增加互动,促进合作,促进转化研究。结果将与改善表现为睡眠、情感、认知、神经、代谢、内分泌和肿瘤疾病以及职业健康的功能障碍具有健康相关性。
英文摘要
DESCRIPTION (provided by applicant): Partial support is requested for the 15th Gordon Research Conference on Chronobiology, to be held on May 6- 11, 2007, at the Centre Paul Langevin, Aussois, France. In recent years, the significance of internal body clocks (circadian clocks) in regulating and adjusting temporal physiology has become increasingly clear and as a result, much effort has been devoted to the analysis of the mechanisms underlying circadian processes. Recognition of the key role played by circadian rhythms in human health and disease, combined with recent landmark discoveries regarding the molecular mechanisms that both generate and regulate the circadian system, has led to a remarkable expansion of the field. Today, chronobiological research attracts a host of researchers from a broad range of disciplines, including neuroscience, molecular genetics, photobiology, computational biology, and metabolism, as well as sleep medicine, psychiatry, oncology, and gerontology. The aims of the Gordon Conference on Chronobiology are: 1) To provide a forum for discussion and for identifying general principles in the rapidly expanding field of chronobiology. 2) To stimulate interactions among researchers working in the various sub-disciplines of chronobiology and thus enhance the coherence of the research field as a whole. 3) To intensify interactions between young and established researchers, and thus sustain high-quality chronobiological research. 4) To promote both national and international collaboration by bringing together scientists from many different research groups and countries. 5) To promote translational research by bringing together investigators employing model organisms with those studying human subjects in circadian research. The conference will achieve these goals by assembling approximately 150 scientists encompassing individuals from different countries, age groups, genders, and using different research models. The program will focus on new and emerging developments in key research areas (see Tentative Program). In accordance with the highly successful Gordon Conference format, lectures will be presented in 8 morning and evening sessions with ample time for discussion. Four poster sessions will allow participants to present additional data. Special attention has been given to achieving gender balance (see discussion leaders) and to including experts from very diverse disciplines to achieve a broadly-based understanding of the frontier of our science and insights as to future opportunities. Outcomes will have health relevance for ameliorating dysfunctions that manifest as sleep, affective, cognitive, neurological, metabolic, endocrine and oncological disorders and occupational health. Partial support is requested for the 15th Gordon Research Conference on Chronobiology, to be held on May 6-11, 2007, at the Centre Paul Langevin, Aussois, France. Conference objectives are to bring together a diverse group of leading researchers for a program focused on new and emerging developments in key research areas, in order to increase interactions, promote collaboration, and promote translational research. Outcomes will have health relevance for ameliorating dysfunctions that manifest as sleep, affective, cognitive, neurological, metabolic, endocrine and oncological disorders and occupational health.
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Cell-type-specific analysis of the suprachiasmatic nucleus
  • 批准号:
    9425234
  • 项目类别:
  • 资助金额:
    $35.44万
  • 财政年份:
    2017
  • 负责人:
    JOSEPH S TAKAHASHI
  • 依托单位:
Cell-type-specific analysis of the suprachiasmatic nucleus
  • 批准号:
    10210449
  • 项目类别:
  • 资助金额:
    $35.44万
  • 财政年份:
    2017
  • 负责人:
    JOSEPH S TAKAHASHI
  • 依托单位:
Cell-type-specific analysis of the suprachiasmatic nucleus
  • 批准号:
    9750837
  • 项目类别:
  • 资助金额:
    $35.44万
  • 财政年份:
    2017
  • 负责人:
    JOSEPH S TAKAHASHI
  • 依托单位:
Molecular interactions of mammalian circadian clock proteins
  • 批准号:
    8692928
  • 项目类别:
  • 资助金额:
    $30.21万
  • 财政年份:
    2013
  • 负责人:
    JOSEPH S TAKAHASHI
  • 依托单位:
海外基金