Administrative Core
Administrative Core
批准号:
7328075
负责人:
Jerry Roy Mendell
金额:
$31.7万
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-09-15 至 2011-08-31
关键词:
AddressAdjuvantAdrenal Cortex HormonesAdverse effectsAnimalsAntibody FormationB-LymphocytesBioinformaticsBlood CirculationBlood VesselsBusinessesCD8B1 geneCanis familiarisCapsidCathetersClinicalClinical ProtocolsClinical ResearchClinical TrialsCommunicationComplexCytotoxic T-LymphocytesDataDatabasesDistalDoseDystrophinEnsureExtravasationFactor IXGastrocnemius MuscleGene DeliveryGene TransferGenesGoalsGrantGrowth FactorHeadHepatocyteHistocompatibility Antigens Class IHumanHuman ResourcesImmune responseImmunityImmunosuppressionImmunosuppressive AgentsIntramuscularIntramuscular InjectionsInvestigationIsolated limb perfusionLegLimb structureLinkLiver CirculationMacaca mulattaMalignant NeoplasmsMediatingMethodsModelingMonkeysMusMuscleMycophenolate Mofetil/TacrolimusOhioOrgan TransplantationOutcomePatientsPersonal SatisfactionPhasePolypeptide N-acetylgalactosaminyltransferasePopulationPredictive FactorProspective StudiesPurine Synthesis InhibitionReportingResearch PersonnelResolutionRiskSafetySerotypingShapesStagingSurfaceSystemT-Cell ActivationT-LymphocyteTherapeutic immunosuppressionThinkingTimeTransgenesTreatment FailureTreatment ProtocolsUncertaintyUnited States Food and Drug AdministrationUniversitiesVascular Endothelial Growth FactorsVenousViralViruscellular transductioncomputer networkexperiencefemoral arterygene therapyimmunogenicityimprovedmdx mousemicro-dystrophinmuscle strengthnonhuman primatepressureprogramsresponsesizesuccesstargeted deliverytissue tropismvector
中文摘要
行政核心将负责促进项目之间的协作沟通,
核心、指导委员会和赞助商/NINDS工作人员。项目之间的协调将大大
由生物信息学分部协助。生物信息学核心负责人将直接向PI报告
管理核心。该分部将在CCRI内维持一个组织网站,展示
链接到所有项目,并发布所有目标和实现这些目标的进度,包括预期日期
完成度。项目之间的协调也将通过季度面对面的方式保持
项目和核心调查人员之间的会议。保罗·詹森是俄亥俄州立大学的调查员
并将与该项目合作。
行政核心还将由企业助理项目经理(先生)组成。
官员(Schlos女士),生物信息学总监(Yetter先生),以及由所有PI组成的指导委员会
和Co-Pis。希林和施洛斯将监督所有财务方面,耶特将支持与网络有关的
计算机网络链接到中心内的所有活动。
已经建立的生物信息学网络提供了一个综合的通信网络,将
将核心相互结合,并与这笔赠款中的两个项目结合在一起。生物信息学还确保
所有人员都可以访问数据库和电子表格等可解释形式的数据。数据
存储在CCRI内的集中式内部网络驱动器中,可访问所有项目人员。
英文摘要
The Administrative Core will be responsible for facilitating collaborative communication between Projects,
Cores, Steering Committee, and Sponsor/NINDS staff. Coordination between projects will be greatly
assisted by the Bioinformatics subdivision. The head of the Bioinformatics core will report directly to the PI
of the Administrative Core. This subdivision will maintain an organizational website within the CCRI showing
links to all projects with postings of all aims and progress toward their attainment, including expected dates
of completion. Coordination between projects will also be maintained through quarterly face-to-face
meetings between Project and Core investigators. Paul Janssen is an investigator at the Ohio State
University and will be collaborating with the project.
The Administrative Core will also be composed of Assistant Project Manager (Mr. Shilling), a Business
Officer (Ms. Schloss), Bioinformatics Director (Mr. Yetter), and a Steering Committee composed of all Pis
and Co-Pis. Mr. Shilling and Ms. Schloss will oversee all fiscal aspects, and Mr. Yetter will support the webrelated
network of computer links to all activities within the Center.
The already established Bioinformatics Network provides an integrated network of communication that links
together the Cores with each other and with the two projects in this grant. Bioinformatics also ensures that
all personnel have access to the data in interpretable forms such as databases and spreadsheets. The data
is stored in a centralized internal network drive within CCRI with access to all program personnel.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Dual-vector mediated mini-dystrophin restoration of function in mdx model of DMD
-
批准号:8879230
-
项目类别:
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资助金额:$18.31万
-
财政年份:2014
-
负责人:Jerry Roy Mendell
-
依托单位:
Dual-vector mediated mini-dystrophin restoration of function in mdx model of DMD
-
批准号:8770895
-
项目类别:
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资助金额:$21.98万
-
财政年份:2014
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负责人:Jerry Roy Mendell
-
依托单位:
Vascular Delivery of alpha-Sarcoglycan for LGMD2D
-
批准号:8237961
-
项目类别:
-
资助金额:$104.13万
-
财政年份:2011
-
负责人:Jerry Roy Mendell
-
依托单位:
Vascular Delivery of alpha-Sarcoglycan for LGMD2D
-
批准号:8334425
-
项目类别:
-
资助金额:$52.24万
-
财政年份:2011
-
负责人:Jerry Roy Mendell
-
依托单位:
Vascular Delivery of alpha-Sarcoglycan for LGMD2D
-
批准号:8546147
-
项目类别:
-
资助金额:$49.63万
-
财政年份:2011
-
负责人:Jerry Roy Mendell
-
依托单位:
The Implications of Dystrophin-Specific T cells for DMD gene Correction
-
批准号:8032751
-
项目类别:
-
资助金额:$31.63万
-
财政年份:2010
-
负责人:Jerry Roy Mendell
-
依托单位:
Overcoming Immune Barriers to Gene Correction for Duchenne Muscular Dystrophy
-
批准号:8473891
-
项目类别:
-
资助金额:$126.3万
-
财政年份:2010
-
负责人:Jerry Roy Mendell
-
依托单位:
Overcoming Immune Barriers to Gene Correction for Duchenne Muscular Dystrophy
-
批准号:8685775
-
项目类别:
-
资助金额:$127.87万
-
财政年份:2010
-
负责人:Jerry Roy Mendell
-
依托单位:
Overcoming Immune Barriers to Gene Correction for Duchenne Muscular Dystrophy
-
批准号:8294415
-
项目类别:
-
资助金额:$135.4万
-
财政年份:2010
-
负责人:Jerry Roy Mendell
-
依托单位:
Overcoming Immune Barriers to Gene Correction for Duchenne Muscular Dystrophy
-
批准号:8133364
-
项目类别:
-
资助金额:$136.0万
-
财政年份:2010
-
负责人:Jerry Roy Mendell
-
依托单位:
Administrative Core
-
批准号:8032763
-
项目类别:
-
资助金额:$9.17万
-
财政年份:2010
-
负责人:Jerry Roy Mendell
-
依托单位:
Overcoming Immune Barriers to Gene Correction for Duchenne Muscular Dystrophy
-
批准号:7989633
-
项目类别:
-
资助金额:$140.01万
-
财政年份:2010
-
负责人:Jerry Roy Mendell
-
依托单位:
Developing Clinical Outcomes for Gene Transfer
-
批准号:7663824
-
项目类别:
-
资助金额:$17.01万
-
财政年份:2008
-
负责人:Jerry Roy Mendell
-
依托单位:
CLINICAL TRIAL: SIX-MONTH (26 WEEKS) CLINICAL TRIAL OF GENTAMICIN IN DUCHENNE MD
-
批准号:7718632
-
项目类别:
-
资助金额:$0.17万
-
财政年份:2007
-
负责人:Jerry Roy Mendell
-
依托单位:
Developing Clinical Outcomes for Gene Transfer
-
批准号:7509209
-
项目类别:
-
资助金额:$28.1万
-
财政年份:2007
-
负责人:Jerry Roy Mendell
-
依托单位:
Diverse Strategies to Correct the Dystrophin Gene Using Vascular Delivery (U54)
-
批准号:7691714
-
项目类别:
-
资助金额:$211.27万
-
财政年份:2007
-
负责人:Jerry Roy Mendell
-
依托单位:
Diverse Strategies to Correct the Dystrophin Gene Using Vascular Delivery (U54)
-
批准号:7495589
-
项目类别:
-
资助金额:$205.16万
-
财政年份:2007
-
负责人:Jerry Roy Mendell
-
依托单位:
Dystrophin Restoration
-
批准号:7328072
-
项目类别:
-
资助金额:$31.7万
-
财政年份:2007
-
负责人:Jerry Roy Mendell
-
依托单位:
Diverse Strategies to Correct the Dystrophin Gene Using Vascular Delivery (U54)
-
批准号:7907724
-
项目类别:
-
资助金额:$155.53万
-
财政年份:2007
-
负责人:Jerry Roy Mendell
-
依托单位:
Implementing Newborn Screening for Duchenne Muscular Dystrophy in the Community
-
批准号:7406885
-
项目类别:
-
资助金额:$45.0万
-
财政年份:2007
-
负责人:Jerry Roy Mendell
-
依托单位:
海外基金