Molecular Imaging and Targeted Therapy of HER2-Positive

亲和体-AlexaFluor偶联物已经在体外开发和测试。体内研究正在等待我们新的Xenogen成像系统的到来。18F标记仿体分子的方法正在与Dale Kiesewetter合作开发。温敏脂质体已被开发并进行了表征。正在与Anu Puri和Robert Blumenthal合作开发将这些脂质体与靶向分子(ScFv的粘附体)连接的方法。

Affibody-AlexaFluor conjugates have been developed in and tested in vitro. In vivo studies await arrival of our new Xenogen imaging system. Methods for 18F labeling of Affibody molecules are being developed in collaboration with Dale Kiesewetter. Thermosensitive liposomes have been developed and characterized. Methodology for conjugation of these liposomes with targeting molecules (Affibody of scFv) is being developed in collaboration with Anu Puri and Robert Blumenthal.