SALIENCE OR GAIN? COMPARING ACCOUNTS OF NUCLEUS ACCUMBENS FUNCTION

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。根据关于腹侧纹状体在刺激加工中作用的不同假说，伏隔核激活要么代表预期获得(Knutson等人，2001；Schultz，2004)，要么代表一般显著(Berbridge&Robinson，1998；Zink等人，2004)。为了比较这些描述，我们用事件相关功能磁共振扫描参与者，当他们执行修改的货币激励延迟(MID)任务时(Knutson等人，2001)。中期任务包括收益、中性和损失结果，其中一些是概率的，一些是有保证的。我们还探讨了参与者在完成任务时的预期中的自我报告唤醒和效价。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. According to distinct hypotheses about the role of the ventral striatum in incentive processing, nucleus accumbens activation represents either anticipated gain (Knutson et al., 2001; Schultz, 2004) or general salience (Berridge & Robinson, 1998; Zink et al., 2004). In order to compare these accounts, we scanned participants with event-related fMRI as they performed a modified monetary incentive delay (MID) task (Knutson et al., 2001). The MID task included gain, neutral, and loss outcomes, some of which were probabilistic and some of which were guaranteed. We also probed self-reported arousal and valence during anticipation as participants played the task.