DEVELOPMENT OF A GUINEA PIG BRAIN ATLAS

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。豚鼠是在各种应用中优先使用的另一种动物模型。然而，目前还没有准确的豚鼠脑磁共振图谱。与我们的小鼠大脑研究类似，我们已经开始使用750MHz仪器对切除的豚鼠大脑进行数据采集。这需要更大的射频线圈（由资源构建）来优化信噪比，并修改标准小鼠成像协议。数据采集是最近才开始的。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The guinea pig is another animal model used preferentially to other models for a variety of applications. However an accurate MR atlas of the guinea pig brain is not available. In a similar fashion to our mouse brain studies, we have begun data acquisition on excised guinea pig brains using the 750MHz instrument. This requires larger rf coils (constructed by the Resource) for optimized SNR, and modifications to the standard mouse imaging protocols. Data acquisition has only recently begun.