DIFFERENCES IN OPIOID-INDUCED HYPERALGESIA AND ANALGESIA

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。确定低剂量（亚镇痛）吗啡是否会增强男性和女性受试者的疼痛敏感性（痛觉过敏）。确定痛觉过敏的程度是否与性别有关。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Determine if low dose (subanalgesic) morphine produces an enhancement of pain sensitivity (hyeralgesia) in male and female subjects. Determine if the magnitude of the hyperalgesia is related to gender.