WIRELESS CAPSULE ENDOSCOPY TO EVALUATE THE SMALL INTESTINE

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。该建议的假设是，诊断为溃疡性结肠炎（UC）、不确定性结肠炎（IC）和克罗恩氏结肠炎（CC）的儿科患者可能存在小肠受累，而之前使用钡剂造影和末端回肠内窥镜检查无法检测到小肠受累。 无线胶囊式内窥镜（WCE）将允许更完整地确定肠道受累的程度，可能导致将诊断从UC或IC重新分类为克罗恩病，并可能改变UC、IC和CC患者的治疗决策。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The hypothesis underlyinlg this proposal is that pediatric patients with diagnoses of ulcerative colitis (UC), indeterminate colitis (IC) and Crohn colitis (CC) may have small bowel involvement that has not been previously detectable using barium contrast radiography and endoscopy of the terminal ileum. Wireless capsule endoscopy (WCE) will allow a more complete determination of the extent of intestinal involvement, potentially leading to reclassification of the diagnosis from UC or IC to Crohn disease, and likely altering therapeutic decisions in patients with UC, IC and CC.