PERIODONTAL INFLAMMATION IN TYPE 1 DIABETES

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。众所周知，1型糖尿病患者的牙周病发病率和严重程度都高于非糖尿病人群。总的来说，糖尿病患者感染的发生率增加，糖尿病患者感染的过程比非糖尿病患者更复杂。本研究的目的是检查中性粒细胞对牙周病合并1型糖尿病患者牙龈炎和牙龈炎的反应。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. It is well established that type 1 diabetics exhibit a greater incidence and severity of periodontal disease that non diabetic populations. Overall, the incidence of infection is increased in patients with diabetes mellitus and infections are most likely to have a complicated course in diabetics that in non diabetic. The objective of this study is to examine the neutrophil response to P. gingivitis and gingivitis in Type I diabetes patients with periodontal disease.