ID OF IMPENDING LT VENTRICULAR DYSFUNCTION IN PTS W SEVERE MITRAL REGURGITATION

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。本研究的目的是探讨无症状严重二尖瓣反流患者运动超声心动图与正常静息心室功能的神经激素激活的相关性，以及运动超声心动图与血浆神经激素水平的比较，以检测无症状严重二尖瓣反流患者即将发生的左心室功能障碍。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purposes of this study are to investigate the correlation between exercise echocardiography and neurohormonal activation in asymptomic patients with severe mitral regurgitation and normal rest ventricular function and comparison of exercise echocardiography to neurohormonal plasma levels for detecting impending left ventricular dysfunction in asymptomatic patients with severe mitral regurgitation.