CRP & HEMODYNAMICALLY SIGNIFICANT ASYMPTOMC EXTRACRANIAL CAROTID ARTERY ATHEROSC

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。血清炎症标志物如c反应蛋白已被确定为外周动脉疾病的预测因子。随着炎症标志物与血管疾病相关的新证据的出现，加上关于非冠状动脉，特别是无症状疾病的数据相对缺乏，本研究旨在评估无症状颈动脉疾病中血清炎症标志物升高的存在。这将为未来的纵向研究奠定基础，以评估血清标志物的效用，以识别那些可能有经历无症状疾病进展风险的患者。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Serum markers of inflammation such as C-reactive protein have been identified as predictors of peripheral arterial disease. With emerging evidence associating inflammatory markers with vascular disease, coupled with the relative paucity of data regarding non-coronary, and particularly asymptomatic disease, this study is designed to assess the presence of elevated serum markers of inflammation in the setting of asymptomatic carotid artery disease. This will lay the groundwork for future longitudinal studies to assess the utility of serum markers to identify those patients that may be at risk to experience asymptomatic progression of disease.