GENERAL CLINICAL RESEARCH CENTER

超出提供的空间。 阿尔伯特·爱因斯坦医学院于1997年9月成立了新的GCRC，位于 学院的主要科学校区和蒙特菲奥里医学中心的大学医院。GCRC 对于医学院的双重使命来说是不可或缺的，即寻找预防和治疗的知识 疾病的治疗和临床研究人员的培训。GCRC支持广泛的 糖尿病、肥胖症、胰岛素抵抗、老龄化、癌症、营养、镰状细胞性贫血、艾滋病毒/艾滋病、 癫痫、关节炎、高胆红素血症、脑代谢、物质滥用和生殖生理，以及 为GCRC提供超过2500万美元的联邦资助研究拨款支持的基础设施 调查人员。我们提交了自第一次申请以来的大量进展记录；例如，37个不同的 这个应用程序中包括项目，是我们第一个应用程序中的两倍，我们遇到或超过了所有 在过去项目期的04年之前，我们的使用率预测。我们还扩展到新的研究领域 NCRR瞄准的地区，现在主办了几个肿瘤学和儿科项目。我们招募了一名 通过a)提供资源和积极鼓励新的 调查人员；b)广泛宣传GCRC、其优秀的病人护理人员及其核心设施；c) 将新的GCRC信息学核心与现有信息系统整合，以提供统计和数据 以灵活和安全的方式为项目提供管理支持；d)建立新的临床研究 内科住院医师培训方案；e)将高级教育与K-30临床相结合 爱因斯坦的研究培训计划；以及，f)专注于爱因斯坦对临床和翻译的扩展 关于GCRC的研究。在本申请中，我们请求额外提供5年的支持，并建议 扩展我们的GCRC核心实验室，以包括分析和磁共振功能，以及 增加患者护理和信息学核心人员，以跟上我们急剧扩大的使用率

EXCEED THE SPACE PROVIDED. The new GCRC at the Albert Einstein College of Medicineestablished in September, 1997is located on the main science campus of the College and the Montefiore Medical Center's University hospital. The GCRC is integral to the twin missions of the College of Medicinethe search for knowledge for the prevention and treatment of disease and the training of clinical investigators.The GCRC supports a broad spectrumof projects in diabetes, obesity, insulin resistance, aging, cancer, nutrition, sickle cell anemia,HIV/AIDS, epilepsy, arthritis, hvperbilirubinemia, brain metabolism, substance abuse, and reproductivephysiology,and provides the infrastructure for over $25 million in Federally-funded research grant support to GCRC investigators. We submit a substantial record of progress since our first application; for example, 37 different projects are included in this application, twice the number in our first application, and we met or exceededall of our utilization projections by year 04 of the past project period. We have also expanded into new research areas targeted by the NCRR, and now host several projects in oncology and pediatrics. We have recruited a wide array ofinvestigators to the Center by a) providing resources and actively encouraging new investigators; b) widely publicizing the GCRC, its outstandingpatient care staff and its Core facilities;c) integrating the new GCRC Informatics core with existing informationsystems to provide statistical and data management support for projects in a flexible and secure fashion; d) establishing a novelclinical research training program for internal medicine residents; e) integrating advanced education with the K-30 Clinical Research Training Program at Einstein; and, f) focusing Einstein's expansion of clinical and translational research aroundltheGCRC. In this application, we request an additional 5 years of support, and propose expanding our GCRC Core Laboratory to include both Analytic and Magnetic Resonance functions, and increment Patient Care and Informatics Core personnel to keep up with our dramatically-expanding utilization