UMMS Clinical and Translational Science

描述（由申请人提供）：NIH路线图计划旨在通过为美国创建综合临床和转化研究计划来加强临床和转化研究企业。我们的提案寻求支持，计划在马萨诸塞州医学院（UMMS）建立一个新的临床和转化科学系（CTSD）。CTSD的使命是为临床研究提供一个“无缝之家”，提供统一的资源：1）招募，教育和培训医生，护士和生物医学科学家进行严格的临床研究; 2）通过培养临床研究者之间的合作文化，加速实验室发现从实验室到临床到社区实践的转变，医疗保健专业人员和基础研究科学家。 这项规划拨款将使我们能够设计一项具有可衡量成果的战略计划，充分利用UMMS及其临床合作伙伴UMass Memorial HealthCare（UMMHC）的强大机构承诺，使我们能够申请NIH未来的临床和转化科学奖。我们的主要目标是：1）评估UMMS当前临床和转化研究的优势和劣势，并制定建立CTSD的计划; 2）制定计划，为CTSD建立统一的治理，整合我们的几个学校，部门和医院; 3）制定一个领导模式，识别转化研究的障碍，评估如何解决这些障碍，并积极促进基础和临床科学家之间的合作; 4）开发新的方法将实验室发现转移到临床和社区实践中，并评估CTSD的使命的成功和失败; 5）开发针对研究生MD，PhD，MD/PhD和护理学生的临床研究的综合培训和教育计划;博士后MD和护理学生;医学和护理学校的初级教师;和继续教育，以支持所有参与临床和转化研究的关键人员; 6）设计方法，促进临床和转化研究以及临床和转化科学家的职业生涯的机构文化的发展。

DESCRIPTION (provided by applicant): The NIH Roadmap Initiative seeks to strengthen the clinical and translational research enterprise by creating an integrated clinical and translational research program for the United States. Our proposal seeks support for planning the establishment of a new Clinical and Translational Science Department (CTSD) at the University of Massachusetts Medical School (UMMS). The mission of the CTSD is to provide a "seamless home" for clinical investigation that provides consolidated resources to: 1) recruit, educate, and train physicians, nurses, and biomedical scientists in rigorous clinical investigation; and 2) to accelerate the movement of laboratory discoveries from bench to bedside to community practice by fostering a culture of collaboration among clinical investigators, healthcare professionals and basic research scientists. This planning grant will allow us to engineer a plan of strategies with measurable outcomes that take full advantage of the strong institutional commitments of UMMS and its clinical partner UMass Memorial HealthCare (UMMHC) to position us to apply for a future Clinical and Translational Science Award from the NIH. Our key objectives are to:1) assess the strengths and weaknesses of current clinical and translational research at UMMS and develop a plan to establish the CTSD; 2) develop a plan to establish cohesive governance for the CTSD that integrates across our several Schools, Departments and Hospitals; 3) develop a leadership model that identifies barriers to translational research, assesses how to address such barriers and actively promotes collaboration between basic and clinical scientists; 4) develop novel ways to move laboratory discoveries into the clinic and into community practice, and to evaluate the successes and failures of the mission of the CTSD; 5) develop comprehensive training and education programs in clinical research directed at graduate MD, PhD, MD/PhD and nursing students; post-doctoral MD and nursing students; junior faculty in the medical and nursing schools; and continuing education to support all key personnel involved in clinical and translational research; 6) devise approaches for the development of an institutional culture which fosters clinical and translational research and the careers of clinical and translational scientists.