Harvard Planning Grant for Institutional Clinical and Translational Science Award

描述（由申请人提供）：我们正在提交一份由哈佛医学院（HMS）和哈佛附属学术健康中心（AHCs）颁发的机构临床和转化科学奖（CTSA）的计划资助申请。哈佛大学致力于为临床研究建立一个学术之家，即哈佛临床与转化科学中心（CISC），该中心将整合哈佛大学的资源，促进富有成效的跨学科合作，通过路线图T32和k12计划促进成功的职业发展，将研究人员与潜在变革技术的专家联系起来，如基因组学、先进成像和生物工程，为有前途的研究提供试点资助。跨学科研究，并普遍加快科学见解转化为有益的临床护理。在本提案中，我们描述了我们对CISC的愿景，以及建立其治理、管理、内容和评估的规划过程。哈佛的研究资源、教职员工和学员非常出色，但往往是分散和孤立的。我们的CTSC将寻求整合整个哈佛的临床研究，以增加新的研究生产力维度，使患者受益。在此过程中，我们将整合和重新调整我们四个独立的普通临床研究中心。信息学将加强中心跨学科和机构之间的联系。这项任务的规模决定了我们必须从规划拨款开始。我们已经成立了一个执行委员会，由哈佛大学临床研究领域的领导者组成，并概述了小组委员会，以解决项目的每个关键组成部分。我们将收集相关资源的清单，并从哈佛内外寻求专家建议。组织顾问将帮助我们确定方案的协同作用和障碍，并帮助确保规划过程达到其里程碑。首席研究员既是一位有成就的临床研究者，也是一位在哈佛大学机构边界工作的长期成功历史的副院长。受托人包括AHC首席执行官和首席学术官以及HMS院长。这些受托人反映了广泛的机构对该计划的承诺，以及指导机构变革和空间和资金投资以承保该计划的权力。我们相信，我们的规划过程是具体的、创新的、有纪律的，应该是稳健的。我们将及时提交一份完整的、有竞争力的CTSA申请。

DESCRIPTION (provided by applicant): We are submitting an application for a Planning Grant for an Institutional Clinical and Translational Science Award (CTSA) from the Harvard Medical School (HMS) and Harvard-affiliated Academic Health Centers (AHCs). Harvard is committed to establishing an academic home for clinical research, the Harvard Clinical and Translational Science Center (CISC), that will integrate resources across Harvard, facilitate productive interdisciplinary collaborations, foster successful career development through Roadmap T32 and K12Programs, link investigators with experts in potentially transformative technologies, such as genomics, advanced imaging, and bioengineering, provide pilot grant support for promising, interdisciplinary research, and generally speed translation of scientific insights into beneficial clinical care. In this proposal we describe our vision for the CISC, and a planning process to establish its governance, administration, content, and evaluation. Harvard's research resources, faculty, and trainees are extraordinary but frequently dispersed and isolated. Our CTSC will seek to integrate clinical research across Harvard to add new dimensions of research productivity benefiting patients. In the process we will integrate and realign our four separate General Clinical Research Centers. Informatics will reinforce the CTSC's links across disciplines and institutions. The magnitude of this task dictates that we start with a planning grant. We have constituted an Executive Committee composed of Harvard's leaders in clinical research and outlined subcommittees to address each of the critical components of the program. We will assemble an inventory of relevant resources and seek expert advice from within and outside Harvard. An organizational consultant will help us identify programmatic synergies and obstacles and help assure the planning process meets its milestones. The Principal Investigator is both an accomplished clinical investigator and an Associate Dean with a long history of success working across Harvard's institutional boundaries. The Trustees include the AHC CEOs and Chief Academic Officers as well as HMS Deans. These Trustees reflect broad institutional commitment to the Program and the authority to direct institutional change and investments of space and money to underwrite the Program. We believe our planning process is specific, innovative yet disciplined, and should be robust. A full and competitive CTSA application will be produced in a timely manner.