CORTICAL MECHANISMS MEDIATING BILATERAL INTERACTIONS BETWEEN THE UPPER LIMBS

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。“我们在两只手执行截然不同的动作时可以轻松地完成任务，这掩盖了这样一个事实，即上肢的运动有一种强烈的集中趋势。这项研究试图建立调节上肢之间双边互动的皮质机制，并阐明任务背景的操纵如何引起这些机制的功能贡献的变化。这项战略性的基础研究，在神经学上完好的个体身上进行，将增进我们对下行运动路径的双边组织的理解，并将对设计上肢运动康复策略具有深远的重要性。”

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. 'The ease with which we perform tasks in which the two hands execute quite different actions belies the fact that there is a strong tendency for the movements of the upper limbs to be drawn together. This research seeks to establish the cortical mechanisms which mediate bilateral interactions between the upper limbs and to elucidate the manner in which manipulations of task context give rise to changes in the functional contributions of these mechanisms. This strategic basic research, conducted with neurologically intact individuals, will advance our understanding of the bilateral organisation of descending motor pathways and will be of profound importance in designing strategies of motor rehabilitation for the upper limb.