Adherence in Adolescents with HIV: The Impact of Body Dissatisfaction

描述(申请人提供)：鉴于艾滋病毒在年轻人中的流行率不断上升，以及这一人群中服药依从性较差。申请者希望通过检查身体形象、服药依从性和饮食失调之间的关系，来探索对这一人群产生负面影响的因素。具体地说，申请人感兴趣的是，在接受抗逆转录病毒药物治疗的青少年人群中，身体不满意是否造成服药依从性的显著差异，以及这种关系的性质是否受到年龄和/或性别的影响。鉴于对身体的不满与饮食失调之间的密切关系，作为第二个目标，申请人希望审查正在接受药物治疗的艾滋病毒感染青少年的身体不满是否与饮食失调行为(例如，限制性节食、过度运动、补偿行为)有关，以及身体不满与饮食失调之间的关系是否受到年龄和/或性别的调节。此外，申请人希望通过确定身体不满是否局限于可能受到药物副作用影响的特定身体部位来进一步了解这一人群中身体形象的性质。鉴于这项研究的结果可能提供关于身体形象如何影响服药依从性和饮食紊乱的有价值的信息，这些发现可能会导致这一未被研究的领域的未来研究，也可能为心理健康和为艾滋病毒感染青少年提供服务的医疗提供者提供指导，因此，代表了NIH进行改善健康研究的使命。 与公共健康相关：有大量研究研究了与青少年服用处方药相关的因素(例如，社会耻辱、经济状况和大量药片)；然而，很少有研究关注一个人对自己身体或身体形象的感受如何影响这一人群。其他对患有慢性病的青少年进行的研究表明，糟糕的身体形象可能是导致治疗结果不佳的一个因素。此外，糟糕的身体形象一再被证明是饮食失调的预兆，饮食失调会带来许多负面的健康后果。因此，这项研究将提供有关身体形象如何影响艾滋病毒青少年治疗的重要信息。这一人群的身体形象研究严重不足，这些信息对未来的研究和为这一人群提供治疗的医疗机构将是有价值的。

DESCRIPTION (provided by applicant): Given the rising prevalence of HIV in youth in addition to poor medication adherence in this population. The applicant desires to explore factors that are impacting this population negatively, by examining the relationship among body image, medication adherence, and disordered eating. Specifically, the applicant is interested in exploring if body dissatisfaction accounts for a significant amount of variance in medication adherence in a population of adolescents being treated with antiretroviral medications, and if the nature of this relation is moderated by age and/ or gender. Given the strong relation between body dissatisfaction and disordered eating, as a second aim, the applicant would like to examine if body dissatisfaction in adolescents with HIV who are being treated with medication is associated with disordered eating behavior (e.g., restrictive dieting, excessive exercise, compensatory behaviors) and if the relation between body dissatisfaction and disordered eating is moderated by age and/or gender. Additionally, the applicant wants to gain further understanding of the nature of body image within this population by determining if body dissatisfaction is localized to specific body parts that may be impacted by medication side effects. Given that the results of this study could provide valuable information on how body image may be impacting medication adherence and disordered eating, the findings could lead to future research in this understudied area and could also provide guidance for mental health and medical providers serving adolescents with HIV, and thus, is representative of NIH's mission to conduct research that improves health. PUBLIC HEALTH RELEVANCE: There is a great deal of research that has studied factors that are associated with adolescents taking their prescribed medications (e.g., social stigma, finances, and numerous pills); however, there is a dearth of studies looking at how one's feelings about their body or body image may be impacting this population. Other studies that have worked with adolescents with chronic illnesses have suggested that poor body image may be a factor that leads to poor treatment outcomes. Additionally, poor body image has been shown repeatedly to be predictive of eating disorders, which have many negative health outcomes. Therefore, this study will supply important information on how body image may be impacting treatment in adolescents with HIV. Body image in this population is severely understudied and this information will be valuable to future research and medical facilities that provide treatment to this population.