The effect of ART on sexual risk behavior in Chennai, India

描述（由申请人提供）：我们还不知道增加抗逆转录病毒疗法（ART）的使用对发展中国家的风险行为有什么影响。本研究探讨了ART对坦桑尼亚达累斯萨拉姆HIV阳性者性风险行为的影响。在个人开始ART之前和6个月后再次进行定量调查。在定量调查之后，将对选定的参与者进行定性访谈，这些参与者属于三类风险行为变化之一：积极（风险较小），消极（风险较大）或没有变化。定量和定性成分将检查性风险行为以及ART和行为之间可能的中介因素，包括身体健康，心理健康，关系因素，治疗依从性和治疗乐观主义。此外，目前还不清楚谁是在资源匮乏的环境中接受有限的抗逆转录病毒疗法的供应，以及这些人是如何被测试，寻求治疗，并被选中接受ART.A次要的研究目标，从而寻求探索在坦桑尼亚接受抗逆转录病毒疗法的人的特点。这一目标将通过定量、定性和人种学方法来实现。

DESCRIPTION (provided by applicant): We do not yet know what effect increased access to anti-retroviral therapy (ART) will have on risk behavior in the developing world. This study examines the effect of ART on sexual risk behavior among HIV-positive individuals in Dar es Salaam, Tanzania. A quantitative survey will be administered before individuals initiate ART and again 6 months later. Following the quantitative survey, qualitative interviews will be conducted with selected participants who fall into one of three categories of risk behavior change: positive (less risky), negative (more risky), or no change. Both quantitative and qualitative components will examine sexual risk behavior as well as possible mediating factors between ART and behavior including physical health, psychological health, relational factors, treatment adherence, and treatment optimism. In addition, it is unclear who is receiving limited supplies of ART in resource-poor settings and how these people came to be tested, seek treatment, and be selected to receive ART. A secondary research aim thus seeks to explore the characteristics of people receiving ART in Tanzania. This aim will be accomplished through quantitative, qualitative, and ethnographic methods.