Micromechanical Device for Intracochlear Drug Delivery

创新的Rivecwenatomy seovfetlroepamtienngtsanind pcorecvhelenatrinpghsyesniosolorignyeuarnadl mheoalreicnuglalorsbsi. olTohgeysehavdevpanavd whthiellwulatyimfoartenleywbeanedfit 数以百万计的个人。然而，要做到这一点，有必要开发一种安全可靠的 Irmeseecahracnhisemffofrotridsetloiversiingnbaiondtievelcopvoeurnsdastilleocntlgy-treaches mthedriungnedreeliavre.控制系统故障 耳部疾病来自德雷珀实验室的生物医学工程师凭借丰富的经验和专业知识 IiandthEeadreIvneflormareyntwifthederuxgpedretilsieveirnyimnniecroesayrsptehmys，ioalondgyc，lipnhiacriamnascaonlodgsyciaendtisottsolforogmic tshuergMeraysswacilhluesapttisneEeyr，e 评估和完善用于治疗内耳疾病的药物递送系统。该设备将具有 I broad a Tpphleicdaetsioignacnotchepptointecnutidaelsfoarnriemvpollauntitoednizdienvgictehettraetaftsewntitohfinhtehaerimngasltosisd.人类的洞穴的 该装置包含一个外部可编程泵，用于再循环外淋巴液， 我不能让技术人员知道我的位置，因为我知道我的位置，我知道我的位置。 该系统的核心源自德雷珀团队拥有的一种新型药物分配微系统 Itdersmign（oestry，fyaebaricantdedg，raenatdert）esdtedlivoevreyrstyhsetepmas，tcsoenvtearianlinygeatrhse. rTapheutilctrac-omipnoiautnudri，zdeidspdenvsiicamismaechoamnpislemte，，long- 控制电子设备和电源。 IcmoinctrionmuToauchhseirnaeiecmdir，scfuolulfaitdthioecnopnorotfrpoolnsdaylisnatferumesti; o（n3（1）o）efsdcteaovbmelilpsohpusanundrsginicnteatrolfpaprceoercitleoecnumtuhrpehsi; na（n2ed）rdeavtresrlmuoipitnaebnledienfvoteircgcerebraltroeordnm，ic，factor Iceaolnendcstrtrereoalneianicstse，fmtoerelecimmapentlraiysnm，tatanipodeptippointepcrtihifaeytempfoowsrteoarirdsaoncuagrvecieoty; f; ac（na4dn）d（d6ied）vaetveloatphluearneptipsieapsf; elat（yn5t）and bdelevedflfroiucpgaclsoytwoirnapgopewresulsmceoirnvnaotriyor，lafnilminagl， 实验中，使用原型设备将化合物输送到内耳。

IinnovatRivecwenatydseovfetlroepamtienngtsanind pcorecvhelenatrinpghsyesniosolorignyeuarnadl mheoalreicnuglalorsbsi.olTohgeysehavdevpanavcesd wthiellwulatyimfoartenleywbeanedfit millions of individuals. However, for this to occur, it will be necessary to develop a safe and reliable Irmeseecahracnhisemffofrotridsetloivdersiingnbaiondacdtievelcopmapvoeurnsdastildeirleocntlgy-tteormthedriungnedreeliavre. ryThseysgteomal fofrththies ctroelalatmboernatiovfeinner ear disorders. Working together, biomedical engineers from Draper Laboratory with experience and expertise IiandthEeadreIvnefliormpmareyntwoifthderuxgpedretilsieveirnyimnniecroesayrsptehmys,ioalondgyc,lipnhiacriamnascaonlodgsyciaendtisottsolforogmic tshuergMeraysswacilhluesnegttisneEeyr,e evaluate and perfect a drug delivery system for the treatment of inner ear disorders. This device will have Ibroad aTpphleicdaetsioignacnodntchepptointecnlutidaelsfoarnriemvpolauntitoednizdienvgictehethtraetaftimtsewntitohfinhtehaerimngasltosisd. cavity of humans. The device contains an externally-programmable pump to recirculate perilymph, an intracochlear catheter inserted Iicnotnoctehnetrsactaeldabtyiomapctainvietchoromupgohuandcso,cahnledosetonmsoyrs, afomr idxeitnegctcinhgamanbdertrwaintshmeixtteinrngaflloywpraongdrapmremssaubrleindfeolirvmeraytiofn. The core of the system is derived from a novel drug dispensing microsystem that the Draper team has Itdersmign(oende, fyaebaricantdedg,raenatdert)esdtedlivoevreyrstyhsetepmas,tcsoenvtearianlinygeatrhse.rTapheutilctrac-omipnoiautnudri,zdeidspdenvsiicnegismaechoamnpislemte,, long- control electronics, and power supply. IcmoinctrionmuToauchhseirnaeiecmdir,scfuolulfaitdthioecnopnorotfrpoaolnsdaylisnatferumesti;o(n3(1)o)efsdcteaovbmelilpsohpusanundrsginicnteatrolfpaprceoercitleoydmtuhrpehsi;na(n2ed)rdeavtresrlmuoipitnaebnledienfvoteircgcerhaftroeordnm,ic,factor Iceaolnendcstrtreroalneianicstse,fmtoerelecimhapentlraiysnm,tatanipodpnsrpoinepcrtihifaeytempfoaowsrteoarirdsaoncuagrvecieoty;f;ac(na4dn)d(d6ied)vaetveloatphluearntaepimsieapsf;elat(yn5t)andbdelevedflfroiucpgaclsoytwoirnapgopewrereleirsmceoirnvnaotriyor,lafnililminagl, Iexperiments, using prototype devices to deliver compounds to the inner ear.