Training in Mammalian Reproductive Biology

描述(由申请者提供)：该计划的目标是培训一些精选的未来科学家，掌握解决生殖问题的广泛方法，包括分子生物学和有机体生物学。经过这种方式培训的科学家将能够使用一系列广泛的方法来解决现代生殖生物学中的重要基础和应用问题。受训人员将在至少两名培训教师的实验室工作，以确保他们熟练掌握几种最先进的技术。可供学员参加的研究项目范围从使用重组DNA程序的非常基础的研究、基因转移和转基因动物的生产，到应用基础研究来解决生殖生物学中的重大问题，例如开发特定的生化方法来破坏内分泌细胞。博士前实习生(4人)将获得理科学士学位和/或理科学士学位和理科硕士学位。他们将被要求参加一系列严格的课程，以满足个别学生的需求，同时确保在细胞和分子生物学、生物化学、生理学、实验设计和统计方面有足够的背景。这门课程涉及研究动物的科学完整性和福祉。预计这些学生将需要3-5年的时间来完成他们的学位，并将在研究生课程的头两年得到这笔补助金的支持。博士后实习生(2人)应拥有博士学位和/或医学硕士学位。他们将选择有限数量的课程，如规划研究和助学金建议，以弥补他们之前培训中的任何不足。我们的生物伦理学家伯纳德·罗林博士开发了一门名为科学与伦理学的课程，所有学员都必须参加。随着博士后或博士后实习生的进步，她/他将被期望成为一个研究项目的负责人(S)，并负责该项目的规划和执行，以及结果的发布。博士后实习生将接受2-4年的培训，前两年将由这笔赠款支持。计划完成后，学员将有资格在学术界、生物技术或制药公司、人类体外受精诊所或政府研究实验室担任研究科学家的职位。最后，几年前启动了一项严格而成功的吸引少数民族的计划。

DESCRIPTION (provided by applicant): The objective of this Program is to train a few selected future scientists in a broad approach to solving reproductive problems encompassing both molecular and organismic biology. Scientists trained in this manner will be able to use a broad array of approaches to address important basic and applied questions in modern reproductive biology. Trainees will work in the laboratory of at least two of the training faculty to ensure that they are adept in several state-of-the-art techniques. Research projects available for trainee participation range from very basic studies using recombinant DNA procedures, gene transfer and production of transgenic animals to the application of basic research to solve major problems in reproductive biology, such as development of specific biochemical methods for destruction of endocrine cells. Predoctoral trainees (4) will enter the program with a B.S. and/or B.S. plus M.S. degrees. They will be required to take a rigorous schedule of courses tailored to fulfill the needs of individual students while ensuring an adequate background in cell and molecular biology, biochemistry, physiology, grantsmanship, and experimental design and statistics. This course deals with scientific integrity and well being of research animals. It is anticipated that these students will require 3-5 years to complete their degrees and will be supported by this grant for the first two years of their graduate program. Postdoctoral trainees (2) are anticipated to have a Ph.D. degree and/or a D.V.M. degree. They will take a limited number of courses, such as Planning Research and Grant Proposals, to fulfill any deficiencies in their previous training. A course, titled Science and Ethics, developed by our bioethicist, Dr. Bernard Rollin, is required for all trainees. As a pre- or postdoctoral trainee progresses, she/he will be expected to become leader of a research project(s) and be responsible for planning and execution of the project, and publication of the results. Postdoctoral trainees will spend 2-4 years in training, the first two of which will be supported by this grant. After completion of the Program, trainees will be qualified to assume positions as research scientists in the academic community, biotechnology or pharmaceutical companies, human in vitro fertilization clinics, or government research laboratories. Finally, a rigorous and successful plan for attracting ethnic minorities was initiated several years ago.