Posdoctoral Training in Environmental Pathology

描述（由申请人提供） 加州大学戴维斯分校（UC-Davis）的环境病理学项目目前已进入第29个年头，支持兽医病理学实习生的一个亚专业小组，他们的研究和职业兴趣是环境因子对健康的影响。 该计划是由病理学，微生物学和免疫学系（PMI）和比较病理学研究生组管理的疾病发病机制更大的研究培训计划的一部分。 这是一个为期6年的整体计划，导致美国兽医病理学家学院（ACVP）董事会资格和博士学位。学员在完成解剖病理学临床培训后，在毕业和研究计划期间得到支持。 Partcipants接受比较病理学，基础细胞生物学，疾病的细胞和分子基础，以及生化毒理学的培训，并在教师实验室进行研究活动，足以获得博士学位。℃下培训教师是根据他们对人类环境健康问题的研究计划的适用性来选择的。 这一要求是3，三年博士后职位，当与其他资源支持的学生相结合时，形成了博士后专业人员的核心，他们在跨学科和资金充足的培训教师的指导下，存在于自学经验的层次结构中。 还要求是一个博士前的位置，用于在DVM博士少数民族招聘。程序.该培训计划的基础是在加州大学戴维斯分校建立的病理学学科和强大的环境导向研究中心之间的互动，主要是在加州灵长类动物研究中心，健康与环境中心，PMI，分子生物科学和解剖学，生理学和细胞生物学部门（兽医学院），环境毒理学（农业和环境科学学院）和内科学（医学院）。培训采用专门定制的博士学位的格式。在比较病理学学位课程。3至4年的研究计划的前12个月主要用于病理学的高级课程，并通过研讨会和研究实验室的轮换介绍环境研究计划。接下来，学员将在其中一名培训教师的指导下完成论文项目。目前活跃的领域包括生殖毒物、空气污染物造成的危害和环境心脏病学。 背景 这是一个竞争性的继续应用程序的环境病理学的培训计划，已资助了29年。 资金要求支持3个博士后职位和一个博士前职位。 该计划有点独特，因为大多数参与者都有兽医学位，除了研究经验外，它还提供临床兽医病理学培训。 在博士后项目结束时，预计学员将完成博士学位的要求。学位，并有资格获得ACVP认证。 要求为六年博士后培训课程的三年研究部分提供支助。 新的这个应用程序是在合并博士/博士学位的三年研究部分中增加了一个博士前培训名额。D. V. M兽医科学家培训计划。 要求增加博士前的名额，以便利从代表性不足的少数群体中招聘受训人员。 这一应用的新内容还包括：增加了在演讲技巧、文献综述、增加研讨会参与和提供包括微阵列和显微成像设备在内的新研究设施方面提供培训的内容。

DESCRIPTION (provided by applicant) The Environmental Pathology Program at the University of California-Davis (UC-Davis), currently entering its 29th year, supports a subspecialty group of veterinary pathology trainees whose research and career interests are in health effects of environmental agents. This program is a part of a larger research Training Program in Pathogenesis of Diseases administered by the Department of Pathology, Microbiology and Immunology (PMI) and the Graduate Group in Comparative Pathology. This is a 6 year overall program leading to American College of Veterinary Pathologists (ACVP) board eligibility and the Ph.D. trainees are supported during their graduate and research program after completing their clinical training in anatomic pathology. Partcipants receive training in comparative pathology, basic cell biology, the cell and molecular basis of disease, and biochemical toxicology and do research activity in faculty laboratories sufficient to qualify for the Ph.D. degree. Training faculty are selected by the applicability of their research program on human environmental health issues. This request is for 3, three year postdoctoral positions which, when combined with students supported by other resources, forms a core of postdoctoral professionals who exists in a self-teaching hierarchy of experience under the mentorship of an interdisciplinary and well funded training faculty. Also requested is one pre-doctoral position to be used for minority recruitment in the DVM Ph.D. program. The foundation of the training program is the established interaction at UC-Davis between the academic discipline of pathology and strong environmentally-orientated research centers, principally in the California Primate Research Center, the Center for Health and Environment, the Departments of PMI, Molecular Biosciences and Anatomy, Physiology and Cell Biology (Veterinary School), Environmental Toxicology (College of Agriculture and Environmental Sciences), and Internal Medicine (School of Medicine). The training uses the format of a specially-tailored Ph.D. degree program in Comparative Pathology. The first 12 months of the 3 to 4-year research program are spent primarily in advanced coursework appropriate to pathology and an introduction to the environmental research programs through seminars and rotations in research laboratories. Trainees next perform a thesis project under the direction of one of the training faculty. Currently active areas include reproductive toxicants, hazards posed by air pollutants and environmental cardiology. BACKGROUND This is a competing continuation application for a training program in Environmental Pathology that has been funded for 29 years. Funds are requested to support 3 postdoctoral positions and one pre-doctoral position. The program is somewhat unique in that the majority of participants have veterinary medical degrees and it provides training in clinical veterinary pathology in addition to research experience as part of the program. At the end of the postdoctoral program trainees are expected to have completed requirements for the Ph.D. degree and are board eligible for ACVP certification. Support is requested for the three-year research portion of the six-year postdoctoral training curriculum. New to this application is the addition of one pre-doctoral training slot within the three-year research portion of the combined Ph.D./D.V.M veterinary scientist training program. The addition of the pre-doctoral slot is requested to facilitate recruitment of trainees from underrepresented minorities. Also new to this application are the addition of components to provide training in presentation skills, literature reviews, increased seminar participation and the availability of new research facilities including microarray and microimaging equipment.