Clinical Core

临床核心A的主要目的是为ANCA相关小血管炎（SW）患者提供访问权限，以获得生物样本和临床信息，用于本项目的三个拟议项目。接触这一患者群体和不同疾病阶段的患者对于成功完成这些项目至关重要。该患者人群中特别关注的临床阶段包括：缓解、治疗缓解、治疗抵抗、复发和终末期肾病。核心还将负责处理和储存生物样本，以及管理有关同意书、样本标签和储存位置以及疾病阶段和结局临床评估的数据库。核心还将提供研究设计和出版和展示摘要所需的统计专业知识， 手稿组成核心的教职员工长期致力于这一竞技场的研究，并与主要和共同研究者一起发表摘要和手稿，特别关注血管炎领域。

The primary purpose of Clinical Core A is to provide access to patients with ANCA-associated small vessel vasculitis (SW) in order to obtain biological samples in conjunction with clinical information for the use in three of the proposed projects of this program project. Access to this patient population and to patients at different disease stages is critical for the successful completion of these projects. Clinical stages of particular interest in this patient population include: remission, remission on therapy, treatment resistance, relapse and end stage renal disease. The Core will also be responsible for processing and storing biologic samples, as well as managing the database with respect to consent forms, labeling and storage locations of specimens, and clinical assessment of disease stages and outcomes. The Core will also provide the study design and statistical expertise needed to publish and present abstracts and manuscripts. The faculty and staff who comprise the Core have a long term commitment to research in this arena and have well documented track record of publishing abstracts and manuscripts with the principal and co-investigators, with a particular focus in the area of vasculitis.