Mentored Clinical Career Award in Adolescent Substance Abuse

描述（由申请人提供）：候选人Sharon JL Levy，医学博士，公共卫生硕士，波士顿儿童医院青少年药物滥用研究中心副研究员，波士顿儿童医院青少年药物滥用项目医学主任，哈佛医学院（HMS）儿科讲师。她是在青少年中使用尿液药物测试方面的新兴专家，并就该主题发表了原创科学文章和临床评论。Levy博士曾担任两项青少年药物测试研究的首席研究员。在K23奖励期间，Levy博士将被解除临床和行政职责，以便她可以在药物和酒精行为治疗研究方面发展新的知识、技能和经验。她将进行第一阶段的随机尿液药物测试试验，作为有问题使用、滥用或依赖药物或酒精的青少年的治疗辅助。她的长期职业目标是开发，测试和传播一套完整的医疗实践指南，用于青少年物质使用的初级保健管理。在K23奖的支持下，她还将在哈佛大学公共卫生学院完成研究设计和生物统计分析课程，并在青少年药物滥用的精神药理学、毒理学和行为疗法方面接受进一步的培训。约翰·奈特博士将是列维博士的主要导师，他最近获得了R01奖，研究在波士顿儿童医院对吸毒和酗酒的青少年进行简短干预的方法。Levy博士将担任该项目的临床治疗师和依从性协调员，直到药物测试试验开始。这使她处于一个理想的位置来进行拟议的试验，并确保与奈特博士经常联系，奈特博士将经常开会，并在需要时向她提供建议。波士顿儿童医院提供了一个理想的研究和培训环境。它是美国最大的儿科医疗中心，儿童医院最近建立了一个临床研究项目，其任务是培训和协助新的临床研究者。Levy博士在发育和行为儿科学方面的背景，她在教学和培训方面的经验，以及她与国家组织建立的关系，将有助于确保她的研究成果得到尽可能广泛的传播。

DESCRIPTION (provided by applicant): The candidate Sharon JL Levy, MD, MPH is an associate researcher at the Center for Adolescent Substance Abuse Research at Children's Hospital Boston, Medical Director of the Adolescent Substance Abuse Program at Children's Hospital, Boston, and an Instructor of Pediatrics at Harvard Medical School (HMS). She is an emerging expert on the use of urine drug testing with adolescents, and has published original scientific articles and clinical reviews on this topic. Dr. Levy has served as PI of two studies on adolescent drug testing. During the K23 award period, Dr. Levy will be relieved of clinical and administrative responsibilities so that she may develop new knowledge, skills, and experience in drug and alcohol behavioral treatment research. She will conduct a stage I trial of random urine drug testing as a therapeutic adjuvant for adolescents with problem use, abuse or dependence on drugs or alcohol. Her long-term career goal is to develop, test, and disseminate a complete set of medical practice guidelines for the primary care management of adolescent substance use. With support from the K23 award, she will also complete courses in research study design and biostatistical analysis at the Harvard School of Public Health, as well as further training in psychopharmacology, toxicology and behavioral therapies for adolescent substance abuse. Dr. John Knight, who will serve as Dr. Levy's primary mentor, has recently been awarded an R01 award to study the use of a brief intervention with adolescents who are using drugs and alcohol at Children's Hospital, Boston. Dr. Levy will serve as a Clinician-Therapist and the Adherence Coordinator for this project until the drug testing trial begins. This places her in an ideal position to conduct the proposed trial, and ensures frequent contact with Dr. Knight who will be available for frequent meetings as well as to advise her whenever the need arises. Children's Hospital Boston presents an ideal research and training environment. It is the largest pediatric medical center in the U.S. Children's recently established a Clinical Research Program, whose mission is to train and assist new clinical investigators. Dr. Levy's background in Developmental and Behavioral Pediatrics, her experience in teaching and training, and her established relationships with national organizations, will help ensure the widest possible dissemination of her research findings.