Identification and characterization of the molecular mechanisms of cardiac muscle regeneration regulated by the epicardium in zebrafish

心脏病发作是一种危及生命的疾病，会损害心肌。人类心脏在受损后不能产生新的肌肉，这在一定程度上导致了这种疾病的高发病率和死亡率。与人类不同，斑马鱼是一种小型热带淡水鱼，受伤后可以自然产生心肌。在这个项目中，我们将在分子水平上了解斑马鱼是如何再生心肌的，并为修复人类心脏受损的肌肉提供见解。

Heart attack is a life-threatening disease that damages cardiac muscle. The human heart cannot create new muscle after the damage, which partly contributes to the high morbidity and mortality of this disease. Unlike humans, zebrafish, a small tropical freshwater fish, can naturally create cardiac muscle after injury. In this project, we will understand at the molecular level how zebrafish regenerate cardiac muscle, and provide insights for repairing damaged muscle in the human heart.