STIMULI-RESPONSIVE LIPOSOMES

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 我们正在研究响应囊泡（直径约100 nm），其形成囊泡的能力通过化学反应（电子转移）进行操纵。囊泡由磷脂和脂质（脂肪酸）组成，是小的单层囊泡。它们在各种溶液条件下稳定数周，如光散射和场流分馏实验所示。 我们需要使用TEM来证明它们的形状和大小，但由于磷脂/脂质（电子受体）的性质，我们不确定它们在TEM中的稳定性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We are working with responsive vesicles (~100 nm diameter) whose ability to form vesicles is manipulated via chemical reactions (electron transfer). The vesicles are composed of phospholipids and lipids (fatty acids) and are small unilamellar vesicles. They are stable for weeks under a variety of solution conditions, as noted from light scattering and field-flow fractionation expts. We need evidence of their shape and size using TEM, but are unsure of their stability in TEM due to the nature of the phospholipid/lipid (electron acceptor).