X-ray Crystallographic Studies of Human Complement Factor I

结构生物学自然具有吸引力，有助于吸引普通公众对科学的考虑。SML之前曾与学龄儿童(年龄从5岁到18岁不等)讨论过结构如何帮助我们了解使我们生病的病毒和细菌。这项工作可能会产生公众可以接触到的结果，因此，我们将设法抓住一切可能的机会与公众互动并向公众提供信息。我们最近在为科学艺术准备展品方面有经验。在牛津举行的展览发现，基于病原体原子坐标的插图在被这种活动吸引的广大观众中引发了特别激烈的辩论。FI多态在疾病中的作用也将使这项工作引起公众更广泛的兴趣。

Structural biology is naturally attractive and lends itself to drawing the general public into consideration of science. SML has previously talked to school children (ranging in age from 5-18 years) about how structures can help us learn about the viruses and bacteria that make us ill. This work would be likely to generate results that would be accessible for the general public and we would therefore seek to take up all possible opportunities to interact with and inform the general public. We have recent experience in preparing exhibits for an ?Art of Science? exhibition held in Oxford and found that illustrations based on atomic coordinates derived from pathogens provoked particularly lively debate in the wide audience drawn to such an event. The role of FI polymorphisms in disease will also make this work of more general interest to the public at large.