The universal lentiviral packaging cell

遗传性疾病是由患者DNA中的错误引起的。在罕见的遗传性免疫缺陷疾病（泡泡婴儿综合征）的情况下，可以通过使用工程病毒（基因疗法）传递错误DNA的正确副本来治愈。该项目将由UCL MRC/UCL医学分子病毒学中心的科学家进行。他们将开发一种更安全、更有效的方法来生产用于临床基因治疗试验的工程病毒。

Inherited diseases are caused by mistakes in the DNA of patients. In the case of rare inherited immunodeficiencies diseases (Baby in the Bubble syndrome), they can be cured by delivering a correct copy of the faulty DNA using an engineered virus (gene therapy). This project is to be carried out by scientists in the MRC/UCL Medical Molecular Virology Centre at UCL. They will develop a safer and more efficient method to produce engineered viruses for clinical gene therapy trials.