Pulmonary and Critical Care Post-Doctoral Research Training Program

描述(由申请人提供)： 在伊利诺伊大学，我们寻求培训那些完成了两年临床培训，并有能力和承诺再接受两到三年调查培训的肺部和重症监护研究员。我们建议将最少量的相关课堂工作与目标导向的指导研究经验相结合，专注于与炎症和先天免疫在广泛的肺部疾病中的作用相关的科学知识体系。我们认为，这个科学平台最广泛地适用于具有显著炎症特征的各种肺部疾病，包括非常流行的哮喘、COPD和其他烟草引起的肺部疾病、间质性肺部疾病和急性呼吸窘迫综合征。通过设计，我们提出了一个双轨计划，将“临床试验、流行病学和结果研究”的培训与“炎症细胞和动物模型的翻译方法”相结合。被临床科学专业录取的考生将选修4门相关的流行病学和生物统计学课程，被选入基础科学专业的考生将完成研究方法和生物学与生理学相结合的4门课程。导师的选择依据是他们的专业知识和兴趣领域、一套互补的研究技能、外部资助的成就以及经过证明的强有力的指导记录。所有学员将制定个性化的研究计划，学习撰写拨款申请，并在学术就业安置方面接受职业咨询和帮助。研究咨询委员会、内部执行委员会、外部咨询委员会和首席调查员将密切监测受训人员的进展情况。该计划将根据受训者的学习表现来判断是否成功。我们计划的一个独特方面是，临床和基础轨道将紧密结合，以便两个轨道上的个人将发展两个独立的技能集，这将作为更强大的团队合作方法来协同进行肺部疾病的研究。我们的计划旨在伦理和科学负责的环境中强调新颖的分子方法，并坚定地致力于吸引来自代表性不足的少数族裔的个人。(摘要结束)

DESCRIPTION (provided by applicant): At the University of Illinois, we seek to train pulmonary and critical care fellows who have completed two years of clinical training and have the aptitude and commitment for two or three additional years of investigative training. We propose to integrates a minimal amount of relevant classroom work with a goal directed mentored research experience that is focused on a scientific body of knowledge related to the role of inflammation and innate immunity in a wide spectrum of lung diseases. We believe that this scientific platform pertains most broadly to a wide variety of lung diseases that share a prominent inflammatory feature and include the very prevalent diseases of asthma, COPD and other tobacco induced lung diseases, interstitial lung disease, and the acute respiratory distress syndrome. By design, we propose a two-track program that blends training in "clinical trials, epidemiology, and outcomes research" with "translational approaches in cellular and animal models of inflammation". Candidates accepted to the clinical science track will take four courses in relevant epidemiology and biostatistics and candidates chosen for the basic science track will complete four courses in research methods and integrated biology and physiology. Mentors are selected based on their area of expertise and interests, set of complementary research skills, achievement in extramural funding, and proven record of strong mentorship. All trainees will develop an individualized research program, learn to write grant proposals, and receive career counseling and assistance in academic job placement. The progress of the trainees will be closely monitored by a research advisory committee, internal executive committee, external advisory board, and the principal investigator. The program will be judged successful based on the academic performance of the trainees. A unique aspect of our program is that the clinical and basic tracks will be closely integrated so that individuals in both tracks will develop two separate skill sets that will synergize as a more powerful teamwork approach to the investigation of lung disease. Our program is designed to emphasize novel molecular approaches in an ethical and scientifically responsible environment and has a strong commitment to attracting individuals from underrepresented minorities. (End of Abstract)