Watching viral entry into living cells in real-time
Watching viral entry into living cells in real-time
批准号:
G0701057/1
负责人:
David Klenerman
金额:
$38.4万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2008
资助国家:
英国
项目状态:
已结题
起止时间:
2008 至 --
中文摘要
病毒跨越细胞边界感染细胞。我们将使用新的方法直接实时观察跨越细胞边界的病毒,以观察这一重要过程的新细节。我们将了解抗体如何改变或阻止这一过程,这将有助于我们了解抗体如何预防病毒感染。从长远来看,这将使我们能够以更合理的方式设计疫苗,以应对艾滋病毒和流感等传染性疾病。
英文摘要
Viruses cross the cell boundary to infect cells . We will use new methods to directly watch viruses crossing the cell boundary in real-time to observe new details of this important process. We will see how antibodies alter or stop this process and this will help us understand how antibodies prevent viral infection. This will allow us in the long-term to design vaccines in a more rationale way for importatnt diseases such as HIV and flu.
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