The Palm Springs Symposia on HIV/AIDS

描述(申请人提供)：人类免疫缺陷病毒(HIV)是导致获得性免疫缺陷综合症(AIDS)的病原体。据预测，目前全球约有3300万人感染艾滋病毒。虽然我们对艾滋病毒的分子和细胞生物学的了解已经取得了一些重大进展，但我们对艾滋病发病机制的理解仍然不太清楚。尽管做出了许多努力，但疫苗接种尝试基本上都失败了。同样，尽管治疗非常有效，但艾滋病毒对药物产生抗药性的机制还不太清楚。14年来，棕榈泉艾滋病毒/艾滋病专题讨论会一直是聚集专家和青年调查人员讨论艾滋病毒和艾滋病研究的主要国家会议之一。研讨会每年提供不断发展的主题，涵盖发病机制、疫苗和药物开发。2009-2011年的主题分别是“艾滋病毒与免疫系统：回归基础”、“新的药物靶点和耐药机制”和“导致艾滋病的分子机制”。已经确定了20位受邀发言者，并接受了他们2009年会议的邀请。同样数量的发言者将被邀请参加随后的会议。继续这一密切的会议对于艾滋病毒/艾滋病调查人员社区共享数据、形成合作以及在消除艾滋病这一疾病方面取得进展具有重要意义。

DESCRIPTION (provided by applicant): The human immunodeficiency virus (HIV) is the causative agent for the acquired immune deficiency syndrome (AIDS). It is predicted that globally approximately 33,000,000 individuals are currently infected with HIV. Although a number of significant advances have been made to our understanding of the molecular and cellular biology of HIV, our understanding of the pathogenesis of AIDS remains less well understood. Despite numerous efforts, vaccination attempts have largely failed. Likewise, although therapy is highly effective, the mechanisms by which HIV becomes resistant to drugs are less clearly defined. For fourteen years the Palm Springs Symposium on HIV/AIDS has been one of the leading national meetings bringing together experts and young investigators to discuss research on HIV and on AIDS. The symposium offers evolving topics on an annual basis that cover pathogenesis, vaccines, and drug development. The topics for 2009-2011 are proposed as "HIV and the Immune System: Back to Basics", "Novel Drug Targets and Mechanisms of Resistance", and "Molecular Mechanisms Leading to AIDS", respectively. Twenty invited speakers have been identified and have accepted their invitations for the 2009 meeting. A similar number of speakers will be invited to subsequent meetings. Continuing this intimate meeting is important for the community of HIV/AIDS investigators to share data, to form collaborations, and to make progress on the elimination of AIDS as an illness.