Biostatistics Core

生物统计学核心为每个SPORE提供统计专业知识和数据管理支持 项目，发展研究计划项目和核心。生物统计学核心的职能 包括制定统计设计和分析计划、数据采集和数据库 开发、数据表单开发和处理、监控数据流、及时性和一致性， 在涉及人类受试者的研究中监测患者安全性，数据分析和解释，手稿 和演示文稿准备以及数据存档。 生物统计核心的主要目标是： 1.与每个SPORE项目团队和发展研究计划合作 实验室、动物和人类研究的项目小组，提供统计数据， 设计方案和可行性评估。 2.为每个项目提供统计分析计划，并开发和评估替代方案 统计数据分析方法。 3.执行统计分析计划。 4.在研究结果的解释和演讲和手稿的准备方面进行合作。 5.提供关系型数据库设计、数据表单开发和数据跟踪、监控 数据的一致性和归档。 6.为核心小组所有成员提供一个机会，通过统计和 数据管理问题。 生物统计学核心的存在确保了每个研究者都能获得统计学专业知识， 包括最先进的数据分析和数据管理资源，并提供一种机制， 一致和兼容的数据处理。该核心建立在创新和经过时间考验的程序之上 和系统开发的一个最大的统计小组在该国，马约诊所部， 生物统计学，以及国家癌症研究所资助的马约诊所癌症中心统计单位。

The Biostatistics Core provides statistical expertise and data management support for each of the SPORE projects, the Developmental Research Program projects, and the Cores. Functions of the Biostatistics Core include the development of statistical designs and analysis plans, data acquisition and database development, data form development and processing, monitoring data flow, timeliness, and consistency, monitoring patient safety in studies involving human subjects, data analysis and interpretation, manuscript and presentation preparation, and data archiving. The primary objectives of the Biostatistics Core are: 1. To collaborate with each of the SPORE project teams and the Developmental Research Program project teams on the deyelppment of laboratory, animal, and human studies providing statistical design options and feasibility assessments. 2. To provide a statistical analysis plan for each project and to develop and evaluate alternative statistical data analysis methods. 3. To carry out the statistical analysis plan. 4. To collaborate in the interpretation of study results and preparation of presentations and manuscripts. 5. To provide relational database design, data form development and tracking, monitoring of data consistency, and archiving of data. 6. To provide an opportunity for all members of the Core to discuss and work through statistical and data management issues together. The existence of the Biostatistics Core assures each investigator access to statistical expertise which includes state of the art data analysis and data management resources as well as provides a mechanism of consistent and compatible data handling. This Core builds upon the innovative and time-tested procedures and systems developed by one of the largest statistical groups in the country, the Mayo Clinic Division of Biostatistics, as well as the NCI-funded Mayo Clinic Cancer Center Statistical Unit.