Training Grant In Radiation Biology

描述(申请人提供)：该培训基金的目的是教授博士后在放射生物学领域进行独立研究，使他们能够在放射肿瘤学和癌症生物学领域做出重大贡献。这一目标将通过多方面的方法来实现，包括1)在范德比尔特大学医学院的实验室中为利用尖端技术和高度协作的方法的杰出科学家提供培训，2)辐射生物学、辐射物理和癌症生物学领域的课程工作，3)旨在促进基础科学家和进行转化研究的临床医生/科学家之间的互动的多学科癌症中心研讨会系列，以及4)多学科部门研讨会系列。此外，学员将接触到范德比尔特的临床肿瘤学环境。该项目目前支持3名博士后实习生，同时招收医学博士和博士，其中大多数人在获得学位后12个月内加入我们的项目。我们希望保持这一水平的支持。该计划目前为一名实习生提供长达3年的资助，使不太精通辐射生物学的实习生能够熟练掌握。培训助学金授课人员完全有资格培养个人成为癌症研究领域的杰出科学家，重点是辐射生物学。他们非常富有成效，在各自的领域都是杰出的领导者。他们是临床医生/科学家和基础科学家的混合体，他们在范德比尔特大学和范德比尔特-英格拉姆癌症中心的临床和基础科学系有联合预约。这些教导者将提供一种多学科、基础广泛的方法来开发癌症研究的新范例。美国癌症协会估计，2005年将有超过70万名男性和65万名女性患上癌症。其中约67%的患者将接受电离辐射治疗，以试图防止今年预计将发生的50万人死亡。我们培训计划的目的是提供足够数量的训练有素的临床医生和科学家，他们可以影响放射治疗的治疗效果。

DESCRIPTION (provided by applicant): The objective of this training grant is to teach Postdoctoral Fellows to perform independent research in the area of Radiation Biology, so that they may make significant contributions to the fields of Radiation Oncology and Cancer Biology. This goal will be accomplished using a multi-faceted approach consisting of 1) providing training in the laboratories of outstanding scientists at Vanderbilt University School of Medicine who utilize cutting edge techniques coupled with highly collaborative approaches, 2) course work in the areas of Radiation Biology, Radiation Physics, and Cancer Biology, 3) multi-disciplinary Cancer Center Seminar Series designed to foster interactions between basic scientists and clinician/scientists who perform translational research, and 4) multi-disciplinary departmental seminar series. In addition, trainees will be exposed to clinical oncology environments at Vanderbilt. This program currently supports 3 Postdoctoral trainees, recruiting both M.D.s and Ph.Ds., the majority of which joined our program within 12 months of obtaining their degree. We wish to maintain this level of support. The program is currently funded to support a trainee for up to 3 years, allowing trainees not be well versed in Radiation Biology to become proficient. Training grant preceptors are well qualified to prepare individuals to become outstanding scientists in the field of cancer research, with a focus on radiation biology. They are extremely productive and are outstanding leaders in their respective fields. They are a mix of clinicians/scientists and basic scientists who have joint appointments in clinical and basic science departments at Vanderbilt University and the Vanderbilt-lngram Cancer Center. These preceptors will provide a multi-disciplinary, broad based approach for developing novel paradigms for cancer research. The American Cancer Society estimates that over 700,000 men and 650,000 women will develop cancer in 2005. Approximately 67% of these patients will be treated with ionizing radiation in an attempt to prevent the estimated 500,000 deaths that will occur this year. The purpose of our training program is provide sufficient numbers of highly trained clinicians and scientists who can impact the therapeutic effectiveness of radiation therapy.