Posdoctoral Training in Environmental Pathology

描述(由申请人提供) 加州大学戴维斯分校(UC-Davis)的环境病理学项目(UC-Davis)目前已进入第29个年头，它支持一个由兽医病理学实习生组成的子专业小组，他们的研究和职业兴趣是环境制剂对健康的影响。该计划是由病理、微生物学和免疫学系(PMI)和比较病理学研究生小组管理的更大的疾病病因学研究培训计划的一部分。这是一项为期6年的总体计划，旨在获得美国兽医病理学家学院(ACVP)董事会的资格，博士生在完成解剖病理学临床培训后，在他们的研究生和研究计划期间得到支持。参与者接受比较病理学、基础细胞生物学、疾病的细胞和分子基础以及生化毒理学方面的培训，并在学院实验室进行足以获得博士学位的研究活动。培训教师是根据他们在人类环境健康问题上的研究计划的适用性来选择的。 这是一个3至3年的博士后职位，当与其他资源支持的学生结合在一起时，构成博士后专业人员的核心，他们在跨学科和资金充足的培训教师的指导下，以自学的经验等级存在。还要求提供一个博士前职位，用于DVM博士项目中的少数族裔招聘。培训计划的基础是加州大学戴维斯分校病理学学科与强大的以环境为导向的研究中心之间的既定互动，主要是在加州灵长类研究中心、健康与环境中心、PMI、分子生物科学和解剖学、生理学和细胞生物学(兽医学院)、环境毒理学(农业与环境科学学院)和内科(医学院)。培训采用了比较病理学中专门定制的博士学位课程的形式。为期3至4年的研究计划的前12个月主要用于与病理学相关的高级课程，并通过研讨会和研究实验室的轮换来介绍环境研究计划。受训者接下来在其中一名培训教师的指导下完成一项论文项目。目前活跃的领域包括生殖毒物、空气污染物造成的危害和环境心脏病学。 背景 这是一个资助了29年的环境病理学培训项目的竞争延续申请。请拨资金支持3个博士后职位和1个博士后职位。该方案的独特之处在于，大多数参与者都拥有兽医学位，除了作为方案的一部分，它还提供临床兽医病理学方面的培训。在博士后项目结束时，学员将完成博士学位的要求，并有资格获得ACVP认证。请求为为期六年的博士后培训课程的三年研究部分提供支助。这项申请的新内容是在博士/兽医科学家联合培训计划的三年研究部分中增加了一个博士前培训时段。要求增加博士前时段，以便利从任职人数不足的少数群体中招聘受训人员。这一应用的另一个新特点是增加了提供陈述技能培训、文献审查、更多的研讨会参与以及包括微阵列和显微成像设备在内的新研究设施的组成部分。

DESCRIPTION (provided by applicant) The Environmental Pathology Program at the University of California-Davis (UC-Davis), currently entering its 29th year, supports a subspecialty group of veterinary pathology trainees whose research and career interests are in health effects of environmental agents. This program is a part of a larger research Training Program in Pathogenesis of Diseases administered by the Department of Pathology, Microbiology and Immunology (PMI) and the Graduate Group in Comparative Pathology. This is a 6 year overall program leading to American College of Veterinary Pathologists (ACVP) board eligibility and the Ph.D. trainees are supported during their graduate and research program after completing their clinical training in anatomic pathology. Partcipants receive training in comparative pathology, basic cell biology, the cell and molecular basis of disease, and biochemical toxicology and do research activity in faculty laboratories sufficient to qualify for the Ph.D. degree. Training faculty are selected by the applicability of their research program on human environmental health issues. This request is for 3, three year postdoctoral positions which, when combined with students supported by other resources, forms a core of postdoctoral professionals who exists in a self-teaching hierarchy of experience under the mentorship of an interdisciplinary and well funded training faculty. Also requested is one pre-doctoral position to be used for minority recruitment in the DVM Ph.D. program. The foundation of the training program is the established interaction at UC-Davis between the academic discipline of pathology and strong environmentally-orientated research centers, principally in the California Primate Research Center, the Center for Health and Environment, the Departments of PMI, Molecular Biosciences and Anatomy, Physiology and Cell Biology (Veterinary School), Environmental Toxicology (College of Agriculture and Environmental Sciences), and Internal Medicine (School of Medicine). The training uses the format of a specially-tailored Ph.D. degree program in Comparative Pathology. The first 12 months of the 3 to 4-year research program are spent primarily in advanced coursework appropriate to pathology and an introduction to the environmental research programs through seminars and rotations in research laboratories. Trainees next perform a thesis project under the direction of one of the training faculty. Currently active areas include reproductive toxicants, hazards posed by air pollutants and environmental cardiology. BACKGROUND This is a competing continuation application for a training program in Environmental Pathology that has been funded for 29 years. Funds are requested to support 3 postdoctoral positions and one pre-doctoral position. The program is somewhat unique in that the majority of participants have veterinary medical degrees and it provides training in clinical veterinary pathology in addition to research experience as part of the program. At the end of the postdoctoral program trainees are expected to have completed requirements for the Ph.D. degree and are board eligible for ACVP certification. Support is requested for the three-year research portion of the six-year postdoctoral training curriculum. New to this application is the addition of one pre-doctoral training slot within the three-year research portion of the combined Ph.D./D.V.M veterinary scientist training program. The addition of the pre-doctoral slot is requested to facilitate recruitment of trainees from underrepresented minorities. Also new to this application are the addition of components to provide training in presentation skills, literature reviews, increased seminar participation and the availability of new research facilities including microarray and microimaging equipment.