Immunology and Infectious Diseases

描述(申请人提供)：本次续签申请旨在为印第安纳大学医学院培养免疫学和传染病研究方面的博士后和博士后研究员以及短期研究生提供支持。免疫学和传染病培训计划的目标是培养受过良好教育的、多样化的研究人员，能够应对国家在传染病、免疫缺陷、自身免疫、过敏性疾病和疫苗领域的健康需求。根据这一国家需要，印第安纳大学在这些领域的培训和研究方面做出了持续的承诺。这包括支持研究生和医学科学家培训方面的新举措，以及为专注于免疫学和微生物疾病的翻译发现、过敏和炎症研究以及艾滋病毒基础研究的中心提供空间和资金。目前的计划在交互式、多学科的医疗中心环境中为学生和研究员提供正式和应用培训。项目教师来自微生物学和免疫学、生物化学和分子生物学、医学和儿科学。这个多学科项目提供分子和细胞生物学方面的培训，并提供研究患者样本和体内疾病模型的机会。该计划的优势包括教师研究的多样性，相关导师和学员发表的高质量出版物的坚实记录，以及外部研究资金。学员受益于该计划内积极、协作的研究环境，包括共同指导的机会。综合培训通过教学课程提供，包括生物伦理学、研究研讨会和会议、特定于项目的期刊俱乐部、赠款和职业研讨会，以及实际操作的教师指导。申请为期5年的项目资金，每年支持3名博士后和3名博士后研究员，以及3名短期实习生。项目奖学金支持通常提供两年。奖学金通常提供给二年级及以上的博士后预科生，同时支持初级和高级博士后研究员的混合。短期实习生是一项倡议的一部分，该倡议旨在将学生从代表性不足的群体过渡到博士培训和学术研究职业。 相关性：免疫学和传染病方面的发现对于理解一些疾病和影响其他学科至关重要。然而，仍然迫切需要新的方法来阻止病原体传播、平息自身免疫性疾病、治疗癌症和抑制过敏性疾病。培养一支在这些领域拥有知识的多元化劳动力队伍至关重要，这仍然是本培训计划的关键目标。

DESCRIPTION (provided by applicant): This renewal application seeks support to train pre- and postdoctoral fellows and short-term graduate students in immunology and infectious diseases research at Indiana University School of Medicine. The Immunology and Infectious Disease Training Program's goal is to develop well-educated, diverse investigators capable of responding to the nation's health needs in the areas of infectious disease, immune deficiencies, autoimmunity, allergic diseases, and vaccines. Consistent with this national need, Indiana University has made a sustained commitment to training and research in these areas. This includes support for new initiatives in graduate and medical scientist training, and space and funding for centers focused on translational discoveries in immunology and microbial diseases, research on allergy and inflammation, and basic research on HIV. The current program offers students and fellows formal and applied training within an interactive, multi-disciplinary medical center environment. Program faculty are drawn from Microbiology and Immunology, Biochemistry and Molecular Biology, Medicine and Pediatrics. This multi-disciplinary program offers training in molecular and cellular biology, and opportunities to study patient samples and in vivo models of disease. Strengths of the program include the diversity of faculty research, solid track records of relevant, quality publications from mentors and trainees, and external research funding. Trainees benefit from the active, collaborative research environment within the program including opportunities for co-mentoring. Comprehensive training is offered through didactic courses including bioethics, research seminars and conferences, program-specific journal clubs, grant and career workshops, and hands-on faculty mentoring. Program funding is requested for 5 years to support 3 pre-doctoral and 3 postdoctoral fellows, and 3 short-term trainees per year. Program fellowship support is typically offered for two years. Fellowships are typically offered to 2nd year and beyond pre-doctoral students, while a mix of junior and senior postdoctoral fellows are supported. Short-term trainees are part of an initiative to transition students from under-represented groups to doctoral training and careers in academic research. RELEVANCE: Discoveries in immunology and infectious diseases have been critical in understanding a number of diseases and in impacting other disciplines. Yet a pressing need remains for new means to thwart pathogen transmission, quell autoimmune diseases, treat cancer, and suppress allergic diseases. The development of a diverse workforce knowledgeable in these areas is critical, and remains key goal of this training program.