UA Center for Systems Biology

描述(由申请人提供)：我们建议在亚利桑那大学建立一个系统生物学中心，以促进最先进的高通量技术的应用，并进一步采用多学科、系统的方法进行生物医学研究。该机构在使用模式生物和遗传分析方面的现有优势构成了一个坚实的基础，可在此基础上扩大对生物学和医学基本问题的调查，以纳入系统方法。这项提议的重点是招聘关键的初级教员，他们将提供系统生物学、计算生物学和生物信息学方面的专业知识，以促进协作的多学科研究。该中心将设在科学学院的分子和细胞生物学系(MCB)，并将与医学院的亚利桑那州癌症中心、农业学院的iPLANT联盟和Bio5研究所建立联系。密歇根州立大学有着合作研究和成功招聘教师的传统，这些教师在校园内建立了牢固的联系。此外，我们在招聘和留住女性教师方面有着良好的记录，我们致力于建设一支多元化的教师队伍。考虑到亚利桑那州大量的西班牙裔和美洲原住民人口，我们在建设少数族裔教师方面处于战略地位。我们提出了以下具体目标：1.招聘：我们建议招聘两名新的教员，他们在系统生物学、计算生物学、生物信息学和/或生物医学研究的组学方法(例如基因组学、蛋白质组学、微阵列分析)的广泛领域进行培训和经验。我们建议特别重视招募妇女和任职人数偏低的少数群体。2.指导：新招募的人员将被分配一个指导委员会，该委员会将就实验室设置、员工招聘、拨款撰写、终身教职期望和任何其他所需的援助提供建议和支持。3.试点项目：为了将新教师迅速融入UA多学科科学社区，我们提出了一个试点项目计划，在该计划中，将从校园内广泛的科学界征求涉及新研究员的合作项目。

DESCRIPTION (provided by applicant): We propose to establish a Center for Systems Biology to promote the application of state of the art high- throughput technologies and further a multidisciplinary, systems approach to biomedical research at the University of Arizona. The existing strengths of the institution in the use of model organisms and genetic analysis forms a strong base on which to expand the investigation of fundamental questions in biology and medicine to incorporate a systems approach. This proposal focuses on the recruitment of key junior faculty who will provide expertise in systems biology, computational biology and bioinformatics to foster collaborative multidisciplinary research. This Center will be based in the Department of Molecular and Cellular Biology (MCB) in the College of Science and will interface with the Arizona Cancer Center in the College of Medicine, the iPlant Consortium in the College of Agriculture, and the Bio5 Institute. MCB has a tradition of collaborative research and successful recruitment of faculty who establish strong ties across campus. Furthermore, we have a strong record in the recruitment and retention of women faculty and we are committed to building a diverse faculty. Given the large Hispanic and Native American populations in Arizona, we are in a strategic position to build our minority faculty. We propose the following Specific Aims: 1. Recruitment: We propose the recruitment of two new faculty members who training and experience in the broad areas of systems biology, computational biology, bioinformatics, and/or 'omics approaches to biomedical research (e.g., genomics, proteomics, microarray analysis). We propose to place special emphasis on the recruitment of women and underrepresented minorities. 2. Mentoring: The new recruit will be assigned a mentoring committee that will provide advice and support concerning lab set-up, staff hiring, grant writing, tenure expectations, and any other assistance needed. 3. Pilot Projects: To quickly integrate the new faculty into the UA multidisciplinary scientific community, we propose a pilot project program in which collaborative projects involving the new investigator will be solicited from the broad scientific community on campus.