A NOVEL BREAST CANCER VACCINE USING IMMUNOSTIMULATORY PEPTIDES

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的目的是确定乳腺癌患者是否具有能够与肽反应的淋巴细胞，所述肽源自与免疫刺激肽结合的肿瘤相关抗原。所有实验将在体外进行，使用从患者外周血中分离的淋巴细胞。 这将为乳腺癌患者的新疫苗设计提供基础。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this study is to determine whether patients with breast cancer possess lymphocytes able to react with peptides, derived from tumor-associated antigens in conjunction with immunostimulatory peptides. All experiments will be performed in vitro, with lymphocytes isolated from patients' peripheral blood. This will provide the basis for a new vaccine design for patients with breast cancer.