Identifying, validating and exploiting a novel dclk1-positive bipotential lung stem cell

干细胞的发现改变了我们对慢性病的认识和治疗方法。与其他器官不同，维持和修复肺的干细胞仍然缺乏特征。我最近发现了一种基因，它标记了一组细胞，这些细胞对肺上皮细胞的重新繁殖有贡献。该项目旨在描述这些人群在肺内稳态期间和肺损伤后的表现，以期将这些发现转化为临床。

The discovery of stem cells has changed our understanding and approach to treating chronic diseases. Unlike other organs, the stem cells that maintain and repair the lung remain poorly characterised. I have recently identified a gene that labels a population of cells which contribute to epithelial repopulation of the lung. This project aims to characterise how this population behaves during lung homeostasis and following lung injury, with a view to translating these findings to the clinic.