Developing a Sustainable Consumer Clearinghouse for Translational Depression and

描述(申请人提供)：翻译研究是卫生保健进步的基石。然而，几十年来，促进研究参与者或消费者与调查人员之间的沟通一直是一个挑战。消费者和研究人员的不同观点导致了研究失败，原因是缺乏研究参与者、误解、污名，甚至担心消费者对研究的误用和滥用。这些挑战对于不同的障碍是独一无二的，在抑郁症和双相情感障碍的研究中可能会加剧，部分原因是抑郁症、双相情感障碍和其他情绪障碍施加的固有行为限制，难以接触到特定疾病状态的消费者，共生障碍的流行，以及目前可用于支持这些联系的少数社区或公共资源。拟议的计划旨在通过创建一个消费者抑郁-双相情感研究信息中心，为抑郁症、躁郁症和情绪研究开发一个开创性的、可持续的计划。该信息交换中心将为研究人员提供与有兴趣参与转化性抑郁症研究的消费者直接联系的机会，并将为消费者提供机会，让他们对这项研究的优先事项、方向和评估拥有发言权。该信息交换中心将建立在全国领先的消费者权益倡导组织之一(抑郁和躁郁症支持联盟)、全国首家综合抑郁中心(密歇根大学综合抑郁中心)以及未来全国抑郁中心网络之间预先存在的合作伙伴关系的基础上。它将采用社交网络战略、社区参与和个性化外联来实现其目标。该计划将在密歇根州和俄亥俄州北部地区启动，评估其有效性，然后通过扩大到国家合作伙伴来使其可持续。 公共卫生相关性：拟议的计划旨在开发一个可持续的计划，以促进抑郁症、躁郁症和情绪研究。消费者抑郁-躁郁症研究信息中心将为研究人员提供机会，以确定有兴趣参与转化性抑郁症研究的消费者，并将为消费者提供机会，让他们在抑郁症研究的优先事项、方向和评估方面拥有发言权。

DESCRIPTION (provided by applicant): Translational research is the cornerstone of health care advances. However, facilitating communication between research participants or consumers and investigators has been a challenge for decades. Divergent consumer and investigator perspectives have led to failed research studies due to lack of research participants, misunderstandings, stigma, and even fear of research misuse and abuse among consumers. These challenges are unique for different disorders, and may be exacerbated in depression and bipolar research, due in part to the inherent behavioral constraints imposed by depression, bipolar, and other mood disorders, difficulty in reaching consumers in specific disease states, the prevalence of co-occurring disorders, and the few community or public resources currently available to support these connections. The proposed program aims to develop a groundbreaking, sustainable program for depression, bipolar and mood research by creating a Consumer Depression-Bipolar Research Clearinghouse. The Clearinghouse would provide researchers the opportunity to link directly with consumers interested in participating in translational depression research, and would provide consumers the opportunity to have a voice in the priorities, direction and evaluation of this research. The Clearinghouse will build upon a pre-existing partnership among one of the nation's leading consumer advocacy groups (Depression and Bipolar Support Alliance), the nation's inaugural Comprehensive Depression Center (University of Michigan Comprehensive Depression Center), and in the future, the National Network of Depression Centers. It will employ social networking strategies, community engagement and personalized outreach to achieve its aims. The program will be launched regionally in Michigan and northern Ohio, evaluated for effectiveness, and then made sustainable through expansion to national partners. PUBLIC HEALTH RELEVANCE: The proposed program aims to develop a sustainable program to promote depression, bipolar and mood research. The Consumer Depression-Bipolar Research Clearinghouse would provide researchers the opportunity to identify consumers interested in participating in translational depression research, and would provide consumers the opportunity to have a voice in the priorities, direction and evaluation of depression research.