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Perinatal exposures, epigenetics, child obesity & sexual maturation

Perinatal exposures, epigenetics, child obesity & sexual maturation
围产期暴露、表观遗传学、儿童肥胖
批准号:
8123330
负责人:
Karen Eileen Peterson
金额:
$19.2万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-08-09 至 2013-03-31

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项目成果

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中文摘要
翻译
描述(由申请人提供):行政核心的总体目标是提供中心活动的监督、协调和整合。具体目标是:1)协调和整合项目和核心的科学目标,跟踪其进展和产出,并根据中心的活动进展情况进行必要的调整;2)进行资源管理规划,以确保项目和核心需求得到满足;3)组织项目和核心领导人的会议,促进互动,并传播外部咨询委员会的建议;4)跟踪职业发展和社区参与计划的进展和成功;以及5)编写中心范围的报告,并与NIEHS、EPA和其他参与研究、培训和社区单位或组织的单位或组织进行沟通。核心将通过一个执行委员会运作,执行委员会由行政核心人员(核心领导/私人助理;核心共同领导和儿科保健专家)以及每个项目和核心的领导人组成。行政核心将确保协调中心的活动,并规划和评估核心和项目内部和之间的资源管理。在定期安排的会议上,执行委员会成员将根据拟议的时间表跟踪研究目标的实现情况,并审查项目和核心的协调和资源需求,以确定在出现需求时最有效地利用基础设施和通信来解决需求。实施中心的项目整合计划是管理核心的核心责任,以利用项目之间的协同潜力,环境生物统计核心,以及整个密歇根研究走廊(由密歇根大学、密歇根州立大学和韦恩州立大学组成)与其他中心和调查人员的合作。核心将与外部咨询委员会和其他利益攸关方互动,以优化研究和翻译产出。最后,行政核心将实施职业发展和培训计划,并确保这些活动与中心的研究项目和环境生物统计核心充分结合 公共卫生相关性:行政核心的目标是监督、协调和整合中心的所有活动,以确保实现每个研究/试点项目和环境生物统计学核心的具体目标,将职业发展和培训与研究相结合,并积极参与外部和利益攸关方咨询小组,以促进中心研究的成果和转化。
英文摘要
Description (provided by applicant): The overall goal of the Administrative Core is to provide oversight, coordination, and integration of Center activities. The Specific Aims are to: 1) Coordinate and integrate the scientific aims of the Projects and Cores, track their progress and outputs, and make adjustments as needed as the activities of the Center progress; 2) Conduct resource management planning to assure that Project and Core needs are met; 3) Organize meetings of the Project and Core leaders, facilitate interactions and disseminate recommendations by the External Advisory Committee; 4) Track the progress and success of Career Development and Community Engagement Plans; and 5) Prepare Center-wide reports, and communicate with NIEHS, EPA, and other participating research, training, and community units or organizations. The Core will operate through an Executive Committee composed of Administrative Core personnel (Core Leader/PI; Core Co-Leader and Pediatric Health Specialist) and Leaders of each of the Projects and Cores. The Administrative Core will ensure coordination of Center activities and plan and assess resource management within and across Cores and Projects. At regularly scheduled meetings, Executive Committee members will track accomplishment of research goals according to the proposed timeline, and review coordination and resource needs across the Projects and Cores, to identify the most efficient use of the infrastructure and communications to resolve needs as they arise. Implementation of the Center's Program Integration plan is a central responsibility of the Administrative Core to capitalize on the synergy potential between Projects, the Environmental Biostatistics Core, and with other Centers and investigators throughout the Michigan Research Corridor (made up of UM, Michigan State, and Wayne State Universities). The Core will interact with the External Advisory Board and other Stakeholders to optimize research and translation outputs. Finally, the Administrative Core will implement a Career Development and Training plan and ensure that these activities are fully integrated with the Center's research projects and Environmental Biostatistics Core Public Health Relevance: The goal of the Administrative Core is to oversee, coordinate and integrate all Center activities in order to ensure realization of specific aims for each of the Research/Pilot Projects and the Environmental Biostatistics Core, integration of Career Development & training with research and active engagement with External and Stakeholder Advisory Groups to promote achievement and translation of Center research.
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会议论文
Statistical methods for analysis of high-dimensional mediation pathways
Metabolic Health Risk Among Mid-Life Women: The Roles of Toxicants, Inflammation, and Epigenetics
Metabolic Health Risk Among Mid-Life Women: The Roles of Toxicants, Inflammation, and Epigenetics
Metabolic Health Risk Among Mid-Life Women: The Roles of Toxicants, Inflammation, and Epigenetics
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