课题基金 / 基金详情

Immunotherapeutic Strategies in anti Myeloperoxidase ANCA associated Glomerulonephritis

Immunotherapeutic Strategies in anti Myeloperoxidase ANCA associated Glomerulonephritis
抗髓过氧化物酶 ANCA 相关性肾小球肾炎的免疫治疗策略
批准号:
nhmrc : 1067847
负责人:
Dr Dragana Odobasic
金额:
$41.07万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2016-12-31

项目摘要

项目成果

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中文摘要
翻译
肾脏疾病是澳大利亚第十大最常见的死亡原因。肾小球肾炎(GN)是肾脏疾病的主要原因。在大多数患者中,自身免疫是疾病最严重的形式。在发现作为这种自身免疫的靶点的肽之后,有希望的新生物治疗是可能的。这项资助将评估四种新兴疗法关闭有害自身免疫和治疗疾病的能力。
英文摘要
Kidney disease is the 10th most common cause of death in Australia. Glomerulonephritis (GN) is a major cause of kidney disease. Autoimmunity underpins disease in most patients with the most severe forms. Following the discovery of the peptide that is the target of this autoimmunity promising new biological treatments are possible. This grant will assess the capacity of four emerging therapies to turn off injurious autoimmunity and treat disease.
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会议论文
The role of myeloperoxidase in adaptive immunity and the development of experimental glomerulonephritis and arthritis
  • 批准号:
    nhmrc : 606744
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $35.58万
  • 财政年份:
    2010
  • 负责人:
    Dr Dragana Odobasic
  • 依托单位:
国内基金
海外基金
Scalable Learning and Optimization: High-dimensional Models and Online Decision-Making Strategies for Big Data Analysis