PRIDE SUMMER INSTITUTE IN CARDIOVASCULAR GENETIC EPIDEMIOLOGY

华盛顿大学圣路易斯医学院“心血管遗传流行病学”项目的主要目标是帮助培训和指导来自不同种族群体（特别是少数民族，URM）的青年教师和残疾科学家，使他们在与国家心肺血液研究所（NHLBI）相关的项目领域发展成为独立的研究人员。该项目将扩大遗传流行病学和心血管研究方面的基础培训和强化指导。为此，目前正在进行的SIPID （RFA - HL- 04- 035）暑期学院项目将精简和加强，使用教学指导，调查讲座和动手计算机实验室的混合。具体目标是：在前三年每年招募8名学员，并为他们提供为期3周的第一个暑期学院，随后是为期一年的指导，包括为期2天的年中会议，然后是为期3周的第二次暑期学院。一般来说，将聘用处于职业生涯早期的初级教员和科学家。对于每一个被招募的队列，第一个暑期学院将包括一些关键概念和方法的实践学习，通过与导师和项目主任密切合作，制定职业规划和独立研究计划。随后将进行为期一年的指导，并在年中召开会议，对不断发展的研究计划进行批评。学员们将回到第二届暑期研修班，充分利用参与院校和导师的宝贵资源，主要从事评审、修改和最终确定资助申请草案。将组织模拟研究小组来审查和批评不断发展的赠款，为它们提供充分的反馈，以改进和最终提交资金。该计划的两个亮点是：在暑期学院的大部分时间举行的“集体头脑风暴”会议，所有可用的导师和学员聚集在一起，集体审查、分析和改进学员不断发展的研究计划；以及专门讨论不同教师面临的独特挑战和障碍的特别研讨会。评估和跟踪工具在SIPID项目的环境中已经就位。该计划的有效性将主要通过独立拨款取得的进展来衡量，而出版物的进展被视为成功的次要衡量标准。

The primary goal of the proposed PRIDE (RFA-HL-10-019) program at Washington University in St. Louis, School of Medicine, in "Cardiovascular Genetic Epidemiology" is to help train and mentor junior faculty from diverse ethnic groups (especially Under Represented Minorities, URM) and scientists with disabilities to develop as independent research investigators in an area of programmatic relevance to the National Heart, Lung, and Blood Institute (NHLBI). The program will extend basic training and intensive mentoring in genetic epidemiology and cardiovascular research. Toward this end, the currently ongoing SIPID (RFA - HL- 04- 035) Summer Institute Program will be streamlined and enhanced, using a mix of didactic instruction, survey lectures, and hands-on computer labs. The specific aims deal with: the recruitment of a cohort of 8 mentees during each of the first 3 years and providing them with a 3-week long 1st summer institute, followed by year- long mentoring that includes a 2-day mid-year meeting, followed by a 3-week long 2nd summer institute. In general, junior faculty and scientists in early stages of their careers will be recruited. For each cohort recruited, the 1st summer institute will include hands-on learning of some of the critical concepts and methods, developing career plans and independent research plans by working closely with the mentors and Program Directors. This will be followed by year-long mentoring, with a mid-year meeting to critique the evolving research plans. The mentees will return to the 2nd summer institute which will be devoted largely to critiquing, revising, and finalizing drafts of grant applications, by taking full advantage of the extraordinary resources of the participating institutions and mentors. Mock study sections will be organized to review and critique the evolving grants, providing them with ample feedback for improvement and for eventual submission for funding. Two highlights of the proposed program are: "Group Brainstorming" meetings held on most of the days during the summer institutes where all available mentors and mentees get together to collectively review, analyze, and improve the evolving research plans of the mentees, and the special workshops devoted to unique challenges and barriers faced by diverse faculty. Evaluation and tracking tools are already in place in the context of the SIPID program. Effectiveness of the program will be measured primaily by progress made with independent grants, and with publications progress treated as a secondary measure of success. PUBLIC HEALTH RELEVANCE: Relevance Training a diverse biomedical workforce in state-of-the-art approaches to research in cardiovascular diseases is of considerable public health importance. A highly desirable added benefit is that the trained scientists are more likely to succeed in their research efforts to deal with health disparities among ethnic groups.