GLYCOSCIENCE SKILLS DEVELOPMENT CORE

Glycoscience Skills Core C，Midura）这个NHLBI PEG应用需要构建跨学科研究 在第1年年底前，为最多5名科学家提供糖科学技能。我们将实现这一技能 发展有4个目标：1）教学指导- PEG参与者将参加一个2小时的讲座/期刊 俱乐部每周。这2小时将被细分为45分钟的教职员工主持的讲座 阐述了选定的糖科学主题背后的原则，包括用于 糖胺聚糖和蛋白聚糖的研究。本次教师讲座之后将是一个60分钟的期刊俱乐部 由教员主持，3-4名学生将提出一个10-15分钟的摘要， 文章从糖科学研究中的重要文章的预选列表。整个课程将 在两年期间完成，并将每两年重复一次。2)共享资源核心培训- PEG 参与者将被期望与共享资源核心（“资源核心”）一起安排培训时间。 他们将观察资源核心人员运行特定的分析和技术，然后他们将运行 在Resources Core人员的指导下，用自己的双手完成这些相同的测试。每个参与者 将得到一个详细的分步指南手册的所有共享资源的核心技术，他们将 在完成培训课程后继续。3)正式讲习班培训- PEG参与者将参加 课程在复杂碳水化合物研究中心（CCRC），格鲁吉亚大学（雅典，格鲁吉亚） 在那里，他们将在每年8月和9月举行的正式研讨会上获得实践培训。(4)访问学者 计划- PEG参与者将邀请并在克利夫兰举办一个访问糖科学学者计划 每年3次门诊。其中一个插槽将由邀请教师从CCRC在UGA填补 在克利夫兰诊所停留2.5天另外两个名额将由邀请世界知名的 来自大学以外的教师访问克利夫兰诊所超过2.5天的时间，以满足PEG 参与者和PEG教师每年。除了3个核心C访问学者。核心A将 每年邀请一名外部咨询委员会成员，该成员还将为PEG参与者举办研讨会。 相关性（见说明）： 这项PEG应用将转化糖科学发现，以加强现有的跨学科研究 克利夫兰诊所的心脏、肺和血液研究能力。下一代的研究人员将 为了掌握这些新兴的研究领域，需要在糖科学方面进行教学和实践培训。的 Glycosciences Skills Development Core对于传播此类糖科学知识至关重要。

Glycoscience Skills Core C, Midura) This NHLBI PEG application requires building interdisciplinary research skills in glycosciences for up to five scientist participants by the end of year 1. We will achieve this skill development with 4 objectives: 1) Didactic instruction - PEG participants will attend a 2 h lecture/journal club every other week. These 2 h will be sub-divided into a 45 minute faculty member-mediated lecture delineating the principles behind selected glycoscience topics, including the technologies used in glycosaminoglycan and proteoglycan research. This faculty lecture will be followed by a 60 min journal club facilitated by the faculty member whereby 3-4 students will present a 10-15 min summary of one published article from a pre-selected list of important articles in glycoscience research. The entire curriculum will be completed over a two year period and will repeat every 2 years. 2) Shared Resources Core training - PEG participants will be expected to schedule training time with the Shared Resources Core ("Resources Core"). They wilt observe Resources Core personnel running speciflc assays & technologies, and then they will run these same tests with their own hands under the guidance of Resources Core personnel. Each participant will be given a detailed step-by-step instrucflon manual for all shared resource core techniques that they will keep after completion of their training sessions. 3) Formal workshop training - PEG participants will attend courses at the Complex Carbohydrate Research Center (CCRC), University of Georgia (Athens, Georgia) where they will obtain hands on training in formal workshops held every August & Sept. (4) Visiting scholar program - PEG participants will invite & host a Visiting Glycosciences Scholar program at the Cleveland Clinic 3 times per year. One of these slots will be filled by inviting faculty members from the CCRC at UGA to visit the Cleveland Clinic over a 2.5 day period. The other 2 slots will be filled by inviting world renowned faculty from outside universities to visit the Cleveland Clinic over a 2.5 day period to meet with PEG participants and PEG faculty on an annual basis. In addition to the 3 Core C visiting scholars. Core A will invite annually an External Advisory Board member who will also present a seminar to PEG participants. RELEVANCE (See instmctions): This PEG application will translate glycoscience discoveries to strengthen existing interdisciplinary research capacities in heart, lung & blood research at the Cleveland Clinic. The next generation of investigators will need both didatic & hands on training in glycosciences in order to master these emerging fields of study. The Glycosciences Skills Development Core is critical for disseminating such glycoscience knowledge.