INTEGRATED ENDURANCE AND RESISTANCE EXERCISE COUNTERMEASURES USING A GRAVITY IND

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 当宇航员在太空中因此“失重”时，他们的许多肌肉没有在地球上使用得那么多。这会导致肌肉大小和力量的丧失，以及有氧适应能力的下降。这种力量和体能的丧失是美国国家航空航天局(NASA)非常关注的问题，并促使他们寻找新的锻炼方法来应对这一问题。在太空中，地球上使用的各种机器(或称自由重量)由于缺乏重力而不能工作。NASA正在考虑使用一种新的设备，这种设备可以轻松设置，用于力量训练或有氧自行车。这种紧凑型锻炼设备被称为飞轮锻炼设备，不需要重力就能工作。虽然我们从其他研究中了解到这种设备可以保持甚至增加力量，但还没有人在训练身体有氧和力量系统的计划中使用这种设备。在我们的第一项研究中，我们训练那些在其他方面从事正常活动的人。我们希望看到他们的力量和有氧能力的增加(例如，能够骑得更长或更快)。我们将把它与其他使用地球上通常使用的传统锻炼器材进行训练的人进行比较。这将告诉我们新设备是否同样有效(或更有效)。第二项研究将涉及那些拄着拐杖走路的人来卸掉他们的一条腿。这是一个在太空中发生的事情的模型，那里的腿不需要支撑。与第一项研究一样，这些受试者将使用新设备或传统的锻炼机器进行训练，看看新设备是否可以防止力量丧失和有氧健身。这些研究的结果将验证这种新的锻炼机器在力量训练和有氧体能方面的使用，以便在未来的长期太空飞行中可能使用。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. When astronauts are in space and therefore "weightless" many of their muscles are not used as much as on earth. This can lead to a loss of muscle size and strength as well as a decrease in their aerobic fitness. This loss of strength and fitness is a great concern for NASA (National Astronautics and Space Administration) and has prompted them to look for new exercise methods to counter this problem. In space the kinds of machines (or free weights) that are used on earth do not work due to the lack of gravity. NASA is considering using an new device that can be easily set up to use for strength training or aerobic cycling. This compact exercise device is called the flywheel exercise device and does not require gravity to work. Although we know from other studies that this device can maintain and even increase strength, no one has looked at the use of this device in a program that trains both the aerobic and strength systems in the body. In our first study we train people who are otherwise going about their normal activities. We would expect to see an increase in strength and an increase in their aerobic capacity (e.g., able to cycle longer or faster). We will compare this with other people who train using traditional exercise equipment normally used here on earth. This will tell us if the new device is as (or more) effective. The second study will involve people who walk on crutches to unload one of their legs. This is a model for what happens in space where the legs are not needed for support. As in the first study, these subjects will train using either the new device or traditional exercise machines to see if the new device can prevent loss of strength and aerobic fitness. The results of these studies will validate the use of this new exercise machine for both strength training and aerobic physical fitness for possible use on future long term space flights.