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DETERMINING THE FUNCTIONAL ROLE OF METHYLATION OF PGC1ALPHA

DETERMINING THE FUNCTIONAL ROLE OF METHYLATION OF PGC1ALPHA
确定 PGC1α 甲基化的功能作用
批准号:
8171358
负责人:
Michael R Stallcup
金额:
$0.24万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-09-01 至 2011-08-31

项目摘要

项目成果

Michael R Stallcup的其他基金

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中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金, 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 PGC-1α是一种重要的辅助激活因子,可调节雌激素受体(ER)、糖皮质激素受体(GR)等核受体以及核呼吸因子1(NRF-1)等转录因子的活性。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) has been shown to be an important coactivator that regulates the activity of several nuclear receptors (NR) such as estrogen receptor (ER) and glucocorticoid receptor (GR); as well as transcription factors such as nuclear respiratory factor 1 (NRF-1).
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会议论文
Protein methyltransferases as transcriptional coregulators
  • 批准号:
    8012249
  • 项目类别:
  • 资助金额:
    $13.55万
  • 财政年份:
    2010
  • 负责人:
    Michael R Stallcup
  • 依托单位:
Training in Cellular, Biochemical and Molecular Sciences
  • 批准号:
    7889524
  • 项目类别:
  • 资助金额:
    $7.81万
  • 财政年份:
    2009
  • 负责人:
    Michael R Stallcup
  • 依托单位:
DETERMINING THE FUNCTIONAL ROLE OF METHYLATION OF PGC1ALPHA
  • 批准号:
    7723630
  • 项目类别:
  • 资助金额:
    $0.08万
  • 财政年份:
    2008
  • 负责人:
    Michael R Stallcup
  • 依托单位:
Training in Cellular, Biochemical and Molecular Sciences
  • 批准号:
    7867844
  • 项目类别:
  • 资助金额:
    $19.63万
  • 财政年份:
    2003
  • 负责人:
    Michael R Stallcup
  • 依托单位:
海外基金