Longtitudinal Diabetes Care

候选人：Elasy博士是范德比尔特大学终身医学副教授。他作为转化型（T2）糖尿病研究导师的成功证据主要是他的学员的生产力和外部资金（自2004年以来，他的学员首次撰写了13篇出版物;一份K23资助申请（2005年）和一份待决的K23申请;一个NIDDK少数民族补充他的赠款（R18 DK 062258 -03）和另一个少数民族补充范德比尔特糖尿病研究和培训中心（DRTC P60 DK 020593 -28）。 环境：范德比尔特大学的环境非常有利于POR的开展，范德比尔特明确致力于Elasy博士作为转化糖尿病研究人员和导师的职业生涯。Elasy与K30计划的整合使他能够接触到内分泌学之外的学员，特别是少数民族教师，他们继续进行糖尿病的重点研究。 研究计划：该提案提出了一系列关于维持最佳纵向糖尿病护理所需的最佳糖尿病护理“剂量”的调查。采用随机临床试验，该研究解决了四个具体目标。1）评估3种不同强度的管理方法在达到可接受的血糖控制后预防血糖复发的相对有效性; 2）确定前瞻性预测成功预防复发的患者特征和行为，以更好地了解最有可能对给定维持计划做出反应的目标人群; 3）前瞻性地确定预防血糖复发失败的预测因素，以便更好地识别需要替代维持策略的亚组; 4）使用基于活动的核算确定干预组之间的活动成本差异。 导师计划：除了每周一次的期刊俱乐部，突出研究的方法学方面和两个（一个为医学生/居民/研究员，另一个为初级教师）翻译糖尿病研究人员的每周工作进展会议之外，Elasy博士概述了他的学员将获得的特定技能，超出了一些人将获得的MPH或MSCI学位的正式培训。

The Candidate: Dr. Elasy is a tenured Associate Professor of Medicine at Vanderbilt University . Evidence of his success as a translational (T2) diabetes research mentor is primarily the productivity and external funding of his mentees (13 first authored publications by his mentees since 2004; one K23 funded application (2005) and one pending K23 application; one NIDDK minority supplement to his grant (R18 DK062258-03) and another minority supplement to the Vanderbilt Diabetes Research and Training Center (DRTC P60 DK020593-28). The Environment: The environment at Vanderbilt University is highly conducive to the conduct of POR and Vanderbilt has unequivocally committed to Dr. Elasy's career as both a translational diabetes researcher and mentor. Of note, Dr. Elasy's integration with the K30 program has given him access to mentees, especially minority faculty, outside of Endocrinology who have gone on to do focused research in Diabetes. The Research Plan: This proposal addresses a line of inquiry regarding an optimal "dose" of diabetes care required to sustain optimal longitudinal diabetes care. Employing a randomized clinical trial the study addresses four specific aims. 1)To assess the relative effectiveness of 3 management approaches, varying in intensity, for preventing glycemic relapse after acceptable glycemic control is achieved; 2)To determine patient characteristics and behaviors that are prospectively predictive of successful relapse prevention in order to better understand the target group most likely to respond to a given maintenance plan; 3)To determine prospectively the predictors of failure to prevent glycemic relapse so as to better identify subgroups in need of alternate maintenance strategies; 4)To determine the differences in activity cost between intervention arms using activity based accounting. The Mentoring Plan:ln addition to a weekly journal clubs that highlight the methodological aspects of research and two (one for medical students/residents/fellows and another for junior faculty) weekly work-in-progress sessions for translational diabetes investigators, Dr. Elasy outlines specific skills his mentees will acquire beyond the formal training that some will receive as a result of the MPH or MSCI degree that are available.