Training in Orthopaedic Research

描述(由申请人提供)：罗切斯特大学医学中心肌肉骨骼研究中心的骨科研究培训计划在2006年至今的第一个资助期内蓬勃发展。它已经从来自8个系、司和中心的25名参加培训的教员增加到29名，并在最初阶段成功地招募了一批学生和博士后研究员。该计划的使命仍然是：提供肌肉骨骼科学方面的全面培训，目的是培养骨科研究领域的杰出研究人员。该计划为期6-10年，包括6名博士后和2名博士后实习生的培训时段，围绕这些实习生制定了一个教育计划，提供对骨科调查的全面了解。培训经验旨在培养从最基本的分子研究到人类临床试验的设计和执行等领域的能力，强调研究翻译的概念。该中心和相关的培训教师代表了一个高度整合的导师团队，他们在7个核心研究重点领域提供研究培训机会：骨细胞生物学、软骨生物学和骨关节炎、炎症性骨疾病、骨骼修复、骨癌、骨骼发育和肌肉骨骼临床试验。接受博士前培训的学生被生物医学研究生教育(GEBS)项目录取，该中心已经成为一个受欢迎的目的地，目前有19名学生正在攻读博士学位。此外，中心目前还支持对16名博士后实习生进行高级培训。为了完成我们所宣布的使命，中心已经制定了一个由6项核心活动支持的教育计划：1)中心范围的实验室会议(6个实习生报告/年)，2)整形外科科学课程的综合基础，由3个轮流的讲座组成，重点是方法论、基础骨骼生物学/病理学和“科学的艺术”(例如，拨款和论文写作、有效的演讲、伦理学)，3)两个持续经营的期刊俱乐部，4)助学金写作核心，5)客座教授研讨会系列和6)肌肉骨骼研究研讨会年度中心，邀请一位主讲人。在最初的资助期间，我们能够优化这些核心活动的功能，现在比以前更有能力吸引优秀的年轻科学家加入该计划。总体而言，我们的目标是让他们参与我们的项目，成为他们发展成为互动式骨科研究人员的基石，这些研究人员熟练地将未来的基本发现转化为有效的人类疗法。

DESCRIPTION (provided by applicant): The Training Program in Orthopaedic Research in the Center for Musculoskeletal Research at the University of Rochester Medical Center has thrived during its first funding period from 2006-present. It has grown from 25 to 29 participating training faculty from 8 Departments, Divisions and Centers and it has recruited a successful group of students and post-doctoral fellows during this initial period. The mission of the program continues to be: To provide comprehensive training in musculoskeletal science with the aim of developing outstanding investigators in the field of orthopaedic research. The program for years 6-10 contains training slots for 6 pre-doctoral and 2 post-doctoral trainees and around these trainees is developed an education program that provides a comprehensive understanding of orthopaedic investigation. The training experience aims to build competency in areas ranging from the most basic molecular studies to the design and execution of human clinical trials, stressing the concept of research translation. The Center and associated training faculty represent a highly integrated group of mentors that provide research training opportunities in 7 core research focus areas: bone cell biology, cartilage biology & osteoarthritis, inflammatory bone disease, skeletal repair, bone cancer, skeletal development and musculoskeletal clinical trials. Accepted pre-doctoral trainees matriculate into the Graduate Education in the Biomedical Sciences (GEBS) program, and the Center has become a popular destination with 19 students currently working toward their PhD. In addition, the Center currently supports the advanced training of 16 post-doctoral trainees. To accomplish our stated mission, the Center has developed an education program supported by 6 core activities: 1) Center-wide lab meetings (6 trainee presentations/year), 2) A comprehensive Foundations of Orthopaedic Science Curriculum that is comprised of 3 rotating blocks of lectures focused on methodology, basic skeletal biology/pathology, and the 'Art of Science' (e.g. grant and paper writing, effective presenting, ethics), 3) Two continuously running Journal Clubs, 4) A Grant Writing Core, 5) A visiting professor seminar series and 6) An annual Center for Musculoskeletal Research Symposium with an invited keynote speaker. During the initial funding period, we were able to optimize the function of these Core Activities and are now, even more then before, positioned to attract outstanding young scientists to the program. Overall, we aim to make their involvement in our program the cornerstone to their development into interactive orthopaedic investigators skilled to translate the basic discoveries of the future into effective human therapies.