HISTOLOGY CORE

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 NVCI组织学核心的目标是向内华达州的所有研究者提供形态学、免疫组织化学研究和培养细胞、动物和人体组织原位分析所需的专业知识、设施、技术和技术支持。核心主管是一位美国病理学委员会认证的病理学家和一位受过高水平培训和专业知识的分子实验科学家。他们为研究人员提供咨询，解释组织病理学变化，并确定制备人类和实验动物细胞和组织用于形态学研究的最佳程序。 该中心提供的服务包括：1）常规石蜡包埋组织学，包括特殊组织学染色，2）冷冻和石蜡包埋组织的免疫组织化学，以及mRNA的原位分析，3）组织微阵列分析和4）病理学/形态学解释。这一核心将通过提供单个实验室无法提供的服务来提高研究的生产力，并使研究人员能够专注于自己的项目，而无需开发自己的组织学、生物化学和原位杂交方案。此外，我们还为研究人员提供一致的高质量结果。INBRE奖支持一名半职技术人员和购买小型设备。为了换取这种支持，所有内华达州的研究人员都以折扣价提供组织学服务。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The objective of the Histology Core at NVCI is to make available to all investigators in Nevada, the expertise, facilities, techniques and technical support required for morphological, immunohistochemical studies and in situ analysis of culture cells, animal and human tissues. The core supervisors are an American Board of Pathology certified pathologist and a molecular experimental scientist with high levels of training and expertise. They provide consultation to investigators on interpretation of histopathological changes and identifying optimal procedures for preparing cells and tissue of humans and experimental animals for morphologic studies. The core provides services including: 1) routine paraffin-embedded histology including special histological stains, 2) immunohistochemistry on frozen and paraffin embedded tissues, and in situ analysis of mRNA, 3) tissue micro-array analysis and 4) pathology/morphology interpretation. This core will enhance the productivity of research by providing services not available in individual laboratories and allowing investigators to concentrate on their own projects without the need to develop their own histology, immunohistochemstry and in-situ hybridization protocols. In addition, we also provide consistent, high-quality results to investigators. The INBRE award supports a half-time technician and the purchase of small equipment. In exchange for this support, all Nevada researchers are provided with histology services at a discounted rate.