The Mouse as an Instrument for Ear Research V

描述(由申请者提供)：本申请所要求的资金用于资助将于2012年9月30日至2012年10月4日在缅因州巴尔港的杰克逊实验室举办的“作为耳研究V的工具的鼠标”研讨会的部分资金。这个研讨会是独一无二的，将侧重于在小鼠模型和人类中表征听觉功能的比较和翻译方面的问题。它为研究生、博士后和研究人员提供了一次密集的培训机会，他们希望获得表征老鼠听觉功能的专业知识。这个研讨会是为少数参与者举办的，上午的课堂讲课，下午的实验室课程。这次研讨会的主要目的是促进与听力和平衡相关的生物学领域的研究人员和临床研究人员之间的交流，重点是鼠标在他们的研究领域中实现的和潜在的应用。为此，学生们 来自几个学科的资深研究人员将有机会分享新想法，确定潜在的合作，并帮助规划耳朵研究的未来进程。讲座将在LCC礼堂举行，实践课程将在遗传资源大楼(GRB)的应用基因组学培训中心(AGTC)举行。在老鼠模型资源不断扩大的时代，表型鉴定和相关方法学方面的实践培训将继续为该领域的研究人员带来巨大好处。目前唯一涉及听觉生物学和疾病的教育课程要么专注于人类，要么专注于人类疾病的病理学，而且往往是大型的无定形的社会会议。通常，这些不是真正意义上的研讨会，而是更大的信息活动，通常持续不超过一天。 公共卫生相关性：该研讨会与人类健康直接相关，因为它的重点是使用实验室小鼠来研究和了解人类听觉生物学和疾病。促进负责任地使用适当的模型，对于开发有效的治疗人类听力障碍的新方法至关重要。

DESCRIPTION (provided by applicant): The funds requested in this application are for partial support of the workshop "The Mouse as an Instrument for Ear Research V" to be held at The Jackson Laboratory in Bar Harbor, Maine on September 30, 2012 - October 4, 2012. This workshop is one of a kind and will focus on comparative, translational aspects of characterizing auditory function in mouse models and humans. It represents an intensive training opportunity for graduate students, postdocs and investigators wishing to gain expertise in characterizing mouse auditory function. This workshop is for a small number of participants and includes classroom lectures in the morning, followed by laboratory sessions in the afternoon. It is the primary aim of this workshop to promote communication between both research and clinical investigators in various fields of biology related to hearing and balance, with a focus on the realized and potential applications of the mouse to their field of study. Toward this end, students and established investigators from several disciplines will have an opportunity to share new ideas, identify potential collaborations and help chart a course for the future of ear research. Lectures will be offered in the LCC Auditorium, and hands on sessions will be held in the Applied Genomics Training Center (AGTC) in the Genetic Resources Building (GRB). In an era of expanding mouse model resources, practical training in phenotyping and related methodologies will continue to be of enormous benefit to researchers in the field. The only current educational offerings that address auditory biology and disease either focus on humans or on the pathology of human disease and are often large amorphous society meetings. Typically, these are not workshops in the true sense, but larger informational events often lasting no more than a single day. PUBLIC HEALTH RELEVANCE: This workshop is directly relevant to human health as its focus is on the use of the laboratory mouse to study and understand human auditory biology and disease. Promoting the responsible use of appropriate models is critical to the development of effective new therapeutic approaches to treating human hearing disorders.