The process of long term abstinence from opioid use among HIV+ respondents

描述(由申请人提供)：这项定性研究的重点是70名艾滋病毒+前阿片类药物使用者为保持健康所采用的策略。艾滋病毒+前阿片吸毒者在阿片类药物恢复过程中必须同时应对艾滋病毒血清阳性反应，包括药物管理和机构从属关系，这不仅对个人，而且对他们的家庭/社会网络构成多重挑战。这份重新提交的申请是根据PAR-10-021艾滋病科学轨道奖研究过渡(A-START)由一名早期职业调查员提交的。他在成功吸引街头吸毒者研究方面有很长的历史，现在将重点采访这些艾滋病毒+持续戒毒者，他们已经停止滥用阿片类药物五年或更长时间。非处方阿片类药物的使用和/或滥用，特别是海洛因，(但包括一些药丸形式--奥施康定、维柯丁、潘可定、吗啡，甚至最近的糖浆形式，即“精益”)与高复发率、传染病易感性、刑事司法介入和社会不和谐有关。定性研究人员已经开发了招募和调查活跃使用者的吸毒职业的技术，但经常没有记录不使用的模式。从这项对艾滋病毒血清呈阳性的前阿片类药物使用者进行的探索性初步研究中收集的数据将成为审查艾滋病毒/艾滋病、药物滥用和公共卫生问题交叉问题的更大规模研究的平台。这项研究中的前吸毒者将来自纽约大都会地区，他们都有每日海洛因和/或其他非法阿片类药物使用史超过一年，持续戒断这些物质超过五年，以及通过自我报告衡量的艾滋病毒血清阳性状态。项目小组将通过要求提供文件(例如检测结果、医生的通信、艾滋病毒药物处方等)来核实艾滋病毒状况。开放式访谈的目的是获得描述他们康复过程的信息，并确定其他身体和情感问题的共同发生。疾病控制和预防中心表示，物质使用，主要是阿片类药物的使用，作为艾滋病毒的主要传播途径正在增加。这项研究有望为未来的干预措施提供信息，并勾勒出维持康复和健康的路线图，如艾滋病毒+有生活经验的人/S戒除药物所证明的那样。

DESCRIPTION (provided by applicant): This qualitative study focuses on the strategies 70 HIV+ former opioid users employ to maintain wellness. HIV+ former opioid users who must simultaneously deal with HIV seropositivity, including medication management and institutional affiliation, amid an already difficult process of opioid recovery, pose multiple challenges not only for the individuals but also for their families/social networks. This re- submission application is being submitted under PAR-10-021 AIDS Science Track Award for Research Transition (A-START) by an Early Career Investigator. He has a long history of successfully engaging participants in street drug user studies, and will now focus on interviewing this population of HIV+ sustained abstainers who have ceased their opioid misuse for five or more years. The use of non- prescribed and/or abuse of opioids, particularly heroin, (but including a number of pharmaceutical pill forms - Oxycontin, Vicodin, Percocet, morphine, and even more recent syrup forms, i.e. "Lean") are associated with high relapse rates, infectious disease susceptibility, criminal justice involvement, and social disharmony. Qualitative researchers have developed technologies for recruiting and investigating the drug-using careers of active users, but have not often documented patterns of non-use. The data gathered from this exploratory pilot study of HIV seropositive former opioid users who have been able to maintain abstinence will serve as a platform for larger studies examining the intersection of HIV/AIDS, drug abuse, and public health issues. The former users in this study will be from the New York metropolitan area, all with histories of daily heroin and/or other illicit opioid use exceeding one year, greater than five years sustained abstinence from these substances, and HIV seropositive status as measured by self report. The project team will verify HIV status by asking for documentation (for example test results, correspondence from doctors, prescriptions for HIV medication, etc.). The open ended interview is designed to elicit information describing the process of their recovery as well as ascertain the co-occurrence of other physical and emotional issues. The Centers for Disease Control and Prevention suggests substance use, largely opioid use, is increasing as a primary HIV transmission route. This study holds promise for informing future interventions and sketching a roadmap to maintenance of recovery and wellness as demonstrated by HIV+ people with lived experience/s of abstinence from substance use.